Andreu G, Gautheron A, Nicod-Tran A, Lecrubier C, Samama M
Poste de Transfusion Sanguine, Hôtel-Dieu, Paris.
Ann Med Interne (Paris). 1988;139 Suppl 1:13-7.
When adapted to the Dideco Vivacell cell separator, the eccentriplate system allows preparation of leukocyte-poor platelet concentrates. Results of its use on 84 procedures showed that a mean of 4.51 x 10(11) platelets were removed in less than 2 hours with a particularly low level of leukocyte contamination: 2.6 x 10(8). Study of platelet function showed them to be altered more by eccentriplate than by conventional removal with the same apparatus. Analysis of recirculation in vivo corroborated the functional anomalies observed with all aggregating agents (with the exception of arachidonate). These anomalies were associated with a quantity of platelets collected at the lower limit of French norms: 30% of the concentrates contained less than 4 x 10(11) platelets. These findings indicate the need for improvement in the eccentriplate system.
当适配于迪德科Vivacell细胞分离器时，偏心板系统可用于制备白细胞含量低的血小板浓缩物。在84例手术中使用该系统的结果表明，在不到2小时的时间内平均可去除4.51×10¹¹个血小板，白细胞污染水平特别低：2.6×10⁸。血小板功能研究表明，与使用同一设备进行传统去除相比，偏心板对血小板功能的改变更大。体内再循环分析证实了在所有聚集剂（花生四烯酸盐除外）作用下观察到的功能异常。这些异常与采集的血小板数量处于法国标准下限有关：30%的浓缩物所含血小板少于4×10¹¹个。这些发现表明偏心板系统需要改进。
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