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年轻女性多灶性实质内及胸肌下恶性叶状肿瘤,罕见且不寻常的表现:一例报告

Multifocal intra-parenchymal and sub-pectoral malignant phyllodes tumor in young female, rare and unusual presentation: A case report.

作者信息

Athamnah Mohammad Naser, Abuelaish Omar M, Rabai Nimah A

机构信息

Jordan Board of General Surgery, Jordan Medical Council, Jordan; Breast Surgery Fellowship, San Gerardo Hospital, Milano, Italy; Breast Surgeon, Jordan Ministry of Health, Jordan.

Jordan Board of General Surgery, Jordan Medical Council, Jordan; Fellow of the American College of Surgeons, United States; Breast Surgeon, Jordan Royal Medical Services, Jordan.

出版信息

Int J Surg Case Rep. 2020;71:280-284. doi: 10.1016/j.ijscr.2020.05.014. Epub 2020 May 22.

Abstract

INTRODUCTION

Phyllodes tumors are rare fibroepithelial breast tumors, accounting for less than 1% of all breast tumors. Most Phyllodes tumors are benign. However, about 10% are malignant. The Mean age of presentation for the Malignant Phyllodes tumors is 40 years. This case report describes an unusual presentation of Phyllodes tumor in a young female with an unusual site and presentation of the tumor.

PRESENTATION OF CASE

A 23-year-old female presented with multiple left breast rapidly growing masses. Imaging showed two intra-parenchymal left breast masses and one mass lying posterior to the left pectoralis major muscle, anterior to the chest wall. Diagnosed as phyllodes tumor. Nipple areola sparing mastectomy was performed with excision of the tumor and immediate reconstruction using a silicone implant, followed by radiotherapy.

CONCLUSION

Phyllodes tumor usually presents in patients between 35-55 years old as a single breast mass. Yet, in rare cases, multifocal disease can happen, and disease can present in younger ages. The sub-pectoral presentation of phyllodes tumor is not mentioned in the literature before this case.

摘要

引言

叶状肿瘤是一种罕见的乳腺纤维上皮性肿瘤,占所有乳腺肿瘤的比例不到1%。大多数叶状肿瘤是良性的。然而,约10%是恶性的。恶性叶状肿瘤的平均发病年龄为40岁。本病例报告描述了一名年轻女性叶状肿瘤的不寻常表现,肿瘤的部位和表现都很特殊。

病例介绍

一名23岁女性因左侧乳房多个肿块迅速增大前来就诊。影像学检查显示左侧乳房实质内有两个肿块,一个肿块位于左侧胸大肌后方、胸壁前方。诊断为叶状肿瘤。行保留乳头乳晕的乳房切除术,切除肿瘤,并立即使用硅胶植入物进行重建,随后进行放疗。

结论

叶状肿瘤通常在35至55岁的患者中表现为单个乳房肿块。然而,在罕见情况下,可能会出现多灶性病变,且疾病可能在较年轻的年龄段出现。在本病例之前,文献中未提及叶状肿瘤的胸肌下表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fe5/7264011/f9903c3f08fc/gr1.jpg

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