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[人工晶状体的光谱特性及可见光对视网膜的损伤]

[Spectral characteristics of intraocular lenses and injury to the retina caused by visible light].

作者信息

Egorova E V, Babizhaev M A, Ivanina T A, Zueva M V, Ioshin I E

出版信息

Biofizika. 1988 Nov-Dec;33(6):1035-40.

PMID:3248216
Abstract

It has been shown that intraocular lenses (IOL) prepared from polymethylmethacrylate and silicon let pass the light of short-wave visible and long-wave spectrum regions. Unlike natural lens, IOL have no yellowish coloration, which results in the appearance of chromatic aberrations and brightness of IOL during implantation. Mechanisms of damaging effects of visible light on the retina were studied. It has been shown that a week after the rat eyes were illuminated the waves "a" and "b" ERG were inhibited. At the ultrastructural level damage of the cells of the retinal pigment epithelium and of the retinal layers formed by photoreceptor cells took place. Dynamics of the damage of tissue structures of the retina by visible light was investigated. It is suggested that application of colored lenses and prophylaxis by the inhibitors of free radical oxidation will protect the retina from photochemical damage.

摘要

已经表明,由聚甲基丙烯酸甲酯和硅制成的人工晶状体(IOL)能让短波可见光和长波光谱区域的光通过。与天然晶状体不同,人工晶状体没有泛黄现象,这导致在植入过程中出现色差和人工晶状体的亮度。研究了可见光对视网膜的损伤作用机制。结果表明,大鼠眼睛受光照一周后,视网膜电图的“a”波和“b”波受到抑制。在超微结构水平上,视网膜色素上皮细胞和由光感受器细胞形成的视网膜层细胞发生了损伤。研究了可见光对视网膜组织结构损伤的动态变化。建议使用有色眼镜和用自由基氧化抑制剂进行预防,以保护视网膜免受光化学损伤。

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