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肝移植后无法插管的严重胆肠吻合口狭窄患者会师技术的长期预后

Long-term Outcome of the Rendezvous Technique in Patients With Severe Biliary Anastomotic Stricture That Cannot Cannulate After Liver Transplant.

作者信息

Kim Kyeong Sik, Kim Jong Man, Lee Ji Soo, Choi Gyu Sung, Joh Jae-Won

机构信息

Department of Surgery, Soon Chun Hyang University Seoul Hospital, Seoul, Korea.

Department of Surgery-Transplantation, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

Transplant Proc. 2020 Jul-Aug;52(6):1812-1817. doi: 10.1016/j.transproceed.2020.02.137. Epub 2020 May 29.

Abstract

BACKGROUND

Nearly all publications related to endoscopic treatment of biliary anastomotic stricture after liver transplant have reported cases that can be cannulated. However, very few publications discuss endoscopic treatment of biliary anastomotic stricture (BAS) in which the guide wire does not pass through the stricture site. The purpose of this article is to analyze the long-term outcome of the Rendezvous technique in severe strictures through which guide wires cannot cannulate.

METHODS

Between 2010 and 2017, a total of 29 patients who underwent Rendezvous technique because of severe BAS after liver transplant were included in the study.

RESULTS

Twenty-nine patients who underwent the Rendezvous technique showed a 100% technical success rate. Ten patients (34.4%) required stent removal; the mean stenting period was 14.9 (SD, 5.6) months (range, 6.65-24.14 months). A total of 19 patients were maintained without stent removal; the stent-maintaining period was 13.1 (SD, 8.4) months (range, 3.48-38.61 months). Two patients receiving left lobe grafts maintained the stents for 27.1 (SD, 16.2) months. In left lobe graft, the duct anastomosis position moves to the right posteroinferior side of the patient.

CONCLUSIONS

Our results suggest that the stenting period of the Rendezvous technique was longer in severe BAS than in cannulated endoscopic retrograde cholangiopancreatography cases. Especially in the left liver, the position of the duct anastomosis changed to the right posteroinferior of the patient. Thus, the donor duct and the recipient duct are angulated, kinking worsens, and the stenting period becomes longer.

摘要

背景

几乎所有与肝移植术后胆道吻合口狭窄内镜治疗相关的出版物都报道了能够插管的病例。然而,极少有出版物讨论导丝无法通过狭窄部位的胆道吻合口狭窄(BAS)的内镜治疗。本文的目的是分析会师技术在导丝无法插管的严重狭窄中的长期疗效。

方法

2010年至2017年期间,共有29例因肝移植术后严重BAS而接受会师技术治疗的患者纳入本研究。

结果

29例行会师技术治疗的患者技术成功率为100%。10例患者(34.4%)需要取出支架;平均支架置入期为14.9(标准差,5.6)个月(范围,6.65 - 24.14个月)。共有19例患者未取出支架维持治疗;支架维持期为13.1(标准差,8.4)个月(范围,3.48 - 38.61个月)。2例接受左叶移植的患者支架维持时间为27.1(标准差,16.2)个月。在左叶移植中,胆管吻合位置移至患者右后下侧。

结论

我们的结果表明,在严重BAS中,会师技术的支架置入期比可插管的内镜逆行胰胆管造影病例更长。特别是在左肝,胆管吻合位置变为患者右后下侧。因此,供体胆管和受体胆管成角,扭结加剧,支架置入期变长。

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