肝脏胞质乌头酸酶（ACO1）的鸟类性染色体连锁确认。

Confirmation of avian sex-chromosome linkage of liver cytosolic aconitase (ACO1).

作者信息

Lacson J M, Morizot D C

机构信息

University of Texas M.D. Anderson Cancer Center, Smithville 78957.

出版信息

Cytogenet Cell Genet. 1988;48(4):244-5. doi: 10.1159/000132638.

DOI:10.1159/000132638

PMID:3248382

Abstract

Frequencies of liver cytosolic aconitase (ACO1) allozyme phenotypes in female zebra finches (Poephila guttata) conformed to a sex-chromosome-linked model of inheritance. Since birds are characterized by female heterogamety (ZZ males, ZW females), the observed absence of female heterozygotes for the cytosolic aconitase gene is interpreted as suggesting linkage of the ACO1 locus to the Z chromosome and hemizygous expression of this locus. Confirmation of this linkage assignment provides further support for the concept of evolutionary conservation of the avian Z chromosome.

摘要

雌性斑胸草雀（Poephila guttata）肝脏胞质乌头酸酶（ACO1）同工酶表型的频率符合性染色体连锁遗传模型。由于鸟类的特征是雌性异配性别（ZZ为雄性，ZW为雌性），因此观察到胞质乌头酸酶基因不存在雌性杂合子，这被解释为表明ACO1基因座与Z染色体连锁，且该基因座半合子表达。这一连锁定位的确认进一步支持了鸟类Z染色体进化保守性的概念。