Department of Computer Science, Bahria University, Islamabad, Pakistan.
Department of Computer Engineering, Bahria University, Islamabad, Pakistan.
Curr Med Imaging. 2020;16(5):513-533. doi: 10.2174/1573405615666190129120449.
BACKGROUND: Automated intelligent systems for unbiased diagnosis are primary requirement for the pigment lesion analysis. It has gained the attention of researchers in the last few decades. These systems involve multiple phases such as pre-processing, feature extraction, segmentation, classification and post processing. It is crucial to accurately localize and segment the skin lesion. It is observed that recent enhancements in machine learning algorithms and dermoscopic techniques reduced the misclassification rate therefore, the focus towards computer aided systems increased exponentially in recent years. Computer aided diagnostic systems are reliable source for dermatologists to analyze the type of cancer, but it is widely acknowledged that even higher accuracy is needed for computer aided diagnostic systems to be adopted practically in the diagnostic process of life threatening diseases. INTRODUCTION: Skin cancer is one of the most threatening cancers. It occurs by the abnormal multiplication of cells. The core three types of skin cells are: Squamous, Basal and Melanocytes. There are two wide classes of skin cancer; Melanocytic and non-Melanocytic. It is difficult to differentiate between benign and malignant melanoma, therefore dermatologists sometimes misclassify the benign and malignant melanoma. Melanoma is estimated as 19th most frequent cancer, it is riskier than the Basel and Squamous carcinoma because it rapidly spreads throughout the body. Hence, to lower the death risk, it is critical to diagnose the correct type of cancer in early rudimentary phases. It can occur on any part of body, but it has higher probability to occur on chest, back and legs. METHODS: The paper presents a review of segmentation and classification techniques for skin lesion detection. Dermoscopy and its features are discussed briefly. After that Image pre-processing techniques are described. A thorough review of segmentation and classification phases of skin lesion detection using deep learning techniques is presented Literature is discussed and a comparative analysis of discussed methods is presented. CONCLUSION: In this paper, we have presented the survey of more than 100 papers and comparative analysis of state of the art techniques, model and methodologies. Malignant melanoma is one of the most threating and deadliest cancers. Since the last few decades, researchers are putting extra attention and effort in accurate diagnosis of melanoma. The main challenges of dermoscopic skin lesion images are: low contrasts, multiple lesions, irregular and fuzzy borders, blood vessels, regression, hairs, bubbles, variegated coloring and other kinds of distortions. The lack of large training dataset makes these problems even more challenging. Due to recent advancement in the paradigm of deep learning, and specially the outstanding performance in medical imaging, it has become important to review the deep learning algorithms performance in skin lesion segmentation. Here, we have discussed the results of different techniques on the basis of different evaluation parameters such as Jaccard coefficient, sensitivity, specificity and accuracy. And the paper listed down the major achievements in this domain with the detailed discussion of the techniques. In future, it is expected to improve results by utilizing the capabilities of deep learning frameworks with other pre and post processing techniques so reliable and accurate diagnostic systems can be built.
背景:用于进行无偏诊断的自动化智能系统是色素病变分析的主要需求。在过去几十年中,它已经引起了研究人员的关注。这些系统涉及多个阶段,如预处理、特征提取、分割、分类和后处理。准确地定位和分割皮肤病变是至关重要的。可以观察到,机器学习算法和皮肤镜技术的最新改进降低了错误分类率,因此,近年来人们对计算机辅助系统的关注度呈指数级增长。计算机辅助诊断系统是皮肤科医生分析癌症类型的可靠来源,但人们普遍认为,为了使计算机辅助诊断系统在危及生命的疾病的诊断过程中实际应用,还需要更高的准确性。
简介:皮肤癌是最具威胁性的癌症之一。它是由细胞的异常增殖引起的。核心的三种皮肤细胞是:鳞状细胞、基底细胞和黑素细胞。皮肤癌有两种广泛的类型:黑素瘤和非黑素瘤。良性和恶性黑色素瘤之间很难区分,因此皮肤科医生有时会错误地分类良性和恶性黑色素瘤。黑色素瘤被估计为第 19 种最常见的癌症,它比基底细胞癌和鳞状细胞癌更危险,因为它会迅速扩散到全身。因此,为了降低死亡风险,在早期初级阶段正确诊断癌症类型至关重要。它可以发生在身体的任何部位,但胸部、背部和腿部发生的概率更高。
方法:本文对皮肤病变检测的分割和分类技术进行了综述。简要讨论了皮肤镜及其特征。然后描述了图像预处理技术。本文全面回顾了基于深度学习技术的皮肤病变检测的分割和分类阶段,讨论了文献,并对所讨论的方法进行了比较分析。
结论:在本文中,我们对 100 多篇论文进行了综述,并对最新技术、模型和方法进行了比较分析。恶性黑色素瘤是最具威胁和最致命的癌症之一。几十年来,研究人员一直在努力准确诊断黑色素瘤。皮肤镜下皮肤病变图像的主要挑战是:对比度低、多个病变、边界不规则和模糊、血管、退化、毛发、气泡、斑驳着色和其他类型的变形。缺乏大型训练数据集使得这些问题更加具有挑战性。由于深度学习范式的最新进展,特别是在医学成像方面的出色表现,因此有必要审查深度学习算法在皮肤病变分割中的性能。在这里,我们根据不同的评估参数(如雅可比系数、灵敏度、特异性和准确性)讨论了不同技术的结果,并详细讨论了该领域的主要成果。未来,通过利用深度学习框架的功能以及其他预处理和后处理技术,可以提高结果,从而构建可靠和准确的诊断系统。
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