Huang Z Y
Beijing Tuberculosis and Pulmonary Tumor Institute.
Zhonghua Zhong Liu Za Zhi. 1988 Jul;10(4):280-3.
Pathomorphology of 302 primary bronchogenic adenocarcinomas resected in our hospital from 1957 to 1984 was studied. It consisted of 23.5% of the total lung cancers. Gross findings are: central type 15.9%, peripheral type 82.4%, and disseminated type. 1.7%. Cancerous cavity was observed in 13.2%. According to the histologic classification of lung tumor, WHO, 1981, adenocarcinoma was divided into four subtypes: 1. acinar adenocarcinoma (132 cases); 2. papillary adenocarcinoma (73 cases); 3. bronchiolo-alveolar carcinoma (74 cases) and 4. solid carcinoma with mucus formation (23 cases). Among them, there were 16.6% of scar carcinoma and 1 case associated with asbestosis. 15 cases were studied by electron microscope. The 5-year survival rate was 19.6% (peripheral type 21.7%, central type 12.5% and disseminated type 0%). There was no significant difference in the prognoses of the histologic subtypes. The patients without metastasis to the hilum, mediastinum or positive stump had better prognosis. The relationship between adenocarcinoma and bronchiolo-alveolar carcinoma is discussed.
对我院1957年至1984年切除的302例原发性支气管腺癌的病理形态进行了研究。其占肺癌总数的23.5%。大体所见为：中央型15.9%，周围型82.4%，弥漫型1.7%。13.2%可见癌性空洞。根据1981年世界卫生组织肺肿瘤组织学分类，腺癌分为四个亚型：1. 腺泡腺癌（132例）；2. 乳头状腺癌（73例）；3. 细支气管肺泡癌（74例）；4. 伴有黏液形成的实体癌（23例）。其中，瘢痕癌占16.6%，1例与石棉沉着病相关。对15例进行了电子显微镜检查。5年生存率为19.6%（周围型21.7%，中央型12.5%，弥漫型0%）。各组织学亚型的预后无显著差异。无肺门、纵隔转移或切缘阳性的患者预后较好。并讨论了腺癌与细支气管肺泡癌的关系。
