脉冲氙气紫外线消毒对日本一家医院艰难梭菌表面污染的效果
Effectiveness of pulsed xenon ultraviolet disinfection for Clostridioides (Clostridium) difficile surface contamination in a Japanese hospital.
作者信息
Kitagawa Hiroki, Mori Minako, Hara Toshinori, Kashiyama Seiya, Shigemoto Norifumi, Ohge Hiroki
机构信息
Project Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan; Department of Infectious Diseases, Hiroshima University Hospital, Hiroshima, Japan; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Department of Infection Control, Hiroshima University Hospital, Hiroshima, Japan; Department of Nursing, Hiroshima University Hospital, Hiroshima, Japan.
出版信息
Am J Infect Control. 2021 Jan;49(1):55-58. doi: 10.1016/j.ajic.2020.05.032. Epub 2020 May 30.
BACKGROUND
Contaminated environmental surfaces are important sources of transmission for healthcare-associated pathogens, including Clostridioides (Clostridium) difficile. The effectiveness of manual bleach cleaning and pulsed xenon ultraviolet (PX-UV) disinfection on C. difficile contamination of hospital room high-touch surfaces in Japan was evaluated.
METHODS
The environmental surfaces of 20 C. difficile infection (CDI) isolation rooms were sampled immediately after CDI patients were discharged or transferred. High-touch surfaces were sampled before and after either bleach cleaning or PX-UV disinfection in addition to nonbleach cleaning. Changes in the number of C. difficile-positive samples and bacterial counts for each cleaning method were assessed.
RESULTS
Overall, 286 samples were collected (bleach cleaning, 144 samples; PX-UV disinfection, 142 samples). Before cleaning, the positive rates of C. difficile were 27.8% and 31.0% in bleach cleaning and PX-UV disinfection, respectively. Both bleach cleaning and PX-UV disinfection significantly reduced overall C. difficile-positive samples (P = .018 and P = .002, respectively) and C. difficile colony-forming unit counts (P = .002 and P = .001, respectively).
CONCLUSIONS
PX-UV disinfection in addition to manual nonbleach cleaning effectively reduces C. difficile contamination from high-touch surfaces. Further studies are warranted to evaluate the effect of PX-UV disinfection on CDI rates in Japanese hospitals.
背景
受污染的环境表面是包括艰难梭菌在内的医疗相关病原体的重要传播源。评估了在日本，使用含氯消毒剂人工清洁和脉冲氙气紫外线（PX-UV）消毒对医院病房高接触表面艰难梭菌污染的效果。
方法
在20间艰难梭菌感染（CDI）隔离病房的患者出院或转院后，立即对其环境表面进行采样。除了非含氯消毒剂清洁外，在使用含氯消毒剂清洁或PX-UV消毒前后，对高接触表面进行采样。评估每种清洁方法下艰难梭菌阳性样本数量和细菌计数的变化。
结果
总共收集了286个样本（含氯消毒剂清洁组144个样本；PX-UV消毒组142个样本）。清洁前，含氯消毒剂清洁组和PX-UV消毒组中艰难梭菌的阳性率分别为27.8%和31.0%。含氯消毒剂清洁和PX-UV消毒均显著降低了艰难梭菌阳性样本总数（分别为P = 0.018和P = 0.002）以及艰难梭菌菌落形成单位计数（分别为P = 0.002和P = 0.001）。
结论
除人工非含氯消毒剂清洁外，PX-UV消毒可有效减少高接触表面的艰难梭菌污染。有必要进一步开展研究，以评估PX-UV消毒对日本医院CDI发生率的影响。
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