EMG Service, Local Health Unit "Toscana Sud Est", Siena, Italy.
Department of Medical, Surgical and Neurological Sciences, Neurology-Neurophysiology Unit, University of Siena, Policlinico Le Scotte, Viale Bracci 1, 53100 Siena, Italy.
Neurosci Lett. 2020 Aug 24;734:135107. doi: 10.1016/j.neulet.2020.135107. Epub 2020 May 30.
The objective of the study is to investigate the effects of age, height, gender, body mass index (BMI), waist-to-hip ratio (WHR), arm and elbow measures on ulnar nerve conduction. We enrolled 261 "disease-free" subjects. We analyzed motor conduction velocity (MCV) in across elbow (AE) and forearm tracts, and sensory conduction velocity in 4th, 5th digit-wrist tracts (U4, U5) and in dorsal ulnar cutaneous nerve (DUC). We calculated the amplitudes of sensory and motor potentials (CMAPa and SNAPa), % of CMAPa drop AE, MCV drop and distal motor latency (DML). Univariate and multivariate analyses were performed. We estimated the predictive equations. The median nerve was examined for comparison. Age was negatively correlated with all conduction parameters. Forearm and AE MCV, % of CMAPa drop, DML, U4 and U5 SCV also depended upon height. Females had higher U4 and U5 SNAPa than males. BMI showed inverse relationship with U4 and U5 SNAPa. DUC parameters depended upon BMI and arm length. Similar trends were observed for the median nerve. "Normative" ulnar conduction parameters should be adjusted for demographic and anthropometric measures to improve diagnostic sensitivity.
本研究旨在探讨年龄、身高、性别、体重指数(BMI)、腰臀比(WHR)、手臂和肘部测量值对尺神经传导的影响。我们纳入了 261 名“无病”受试者。我们分析了肘间(AE)和前臂运动传导速度(MCV),以及第 4、5 指-腕部(U4、U5)和尺神经背侧皮支(DUC)的感觉传导速度。我们计算了感觉和运动电位的幅度(CMAPa 和 SNAPa)、AE 处 CMAPa 下降的百分比、MCV 下降和远端运动潜伏期(DML)。进行了单变量和多变量分析。我们估计了预测方程。同时对正中神经进行了检查以作比较。年龄与所有传导参数均呈负相关。前臂和 AE 的 MCV、CMAPa 下降的百分比、DML、U4 和 U5 的 SCV 也与身高有关。女性的 U4 和 U5 的 SNAPa 高于男性。BMI 与 U4 和 U5 的 SNAPa 呈反比关系。DUC 参数取决于 BMI 和臂长。正中神经也表现出相似的趋势。为了提高诊断灵敏度,应根据人口统计学和人体测量学指标对“正常”尺神经传导参数进行调整。