Windsor Alanna M, Kiell Eleanor P, Sobol Steven E
Division of Otolaryngology, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
Department of Otolaryngology, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110122. doi: 10.1016/j.ijporl.2020.110122. Epub 2020 May 19.
Many infants in the neonatal intensive care unit (NICU) require prolonged periods of respiratory support. Microlaryngoscopy and bronchoscopy (MLB) is performed to evaluate for airway pathology and facilitate decision-making regarding further airway interventions or tracheostomy. The objectives of this study are to describe the operative findings of MLB performed on infants in the NICU and determine which pre-operative characteristics or operative findings are predictive of the need for tracheostomy.
The medical records of preterm inpatients in the NICU at a single tertiary care hospital who underwent MLB between January 1, 2013 and January 7, 2016 were reviewed. Baseline and demographic characteristics and intra-operative findings were compared between patients who underwent tracheostomy and those who were successfully weaned from respiratory support.
Seventy-three preterm patients underwent MLB for respiratory failure, of whom 41 (56.2%) underwent tracheostomy. Patients who underwent tracheostomy had lower mean gestational age (27.4 vs. 30.5 weeks), higher prevalence of bronchopulmonary dysplasia (73.2% vs. 37.5%), lower mean birth weight (1.1 kg vs. 1.6 kg), and a greater number of extubation events (5.2 vs. 3.0) than those who weaned from respiratory support. Abnormal MLB findings were common in both groups, though no single MLB finding differed significantly between groups.
Preterm infants in the NICU with gestational age ≤30 weeks, birth weight <1.5 kg, severe pulmonary disease, and who have failed more than 3 extubation attempts are more likely to require tracheostomy.
许多新生儿重症监护病房(NICU)的婴儿需要长时间的呼吸支持。进行微喉镜和支气管镜检查(MLB)以评估气道病变,并有助于就进一步的气道干预或气管切开术做出决策。本研究的目的是描述在NICU对婴儿进行MLB的手术结果,并确定哪些术前特征或手术结果可预测气管切开术的需求。
回顾了一家三级医疗中心医院NICU在2013年1月1日至2016年1月7日期间接受MLB的早产住院患者的病历。比较了接受气管切开术的患者和成功撤机的患者的基线和人口统计学特征以及术中发现。
73例早产患者因呼吸衰竭接受了MLB,其中41例(56.2%)接受了气管切开术。与撤机的患者相比,接受气管切开术的患者平均胎龄更低(27.4周对30.5周),支气管肺发育不良的患病率更高(73.2%对37.5%),平均出生体重更低(1.1kg对1.6kg),拔管事件更多(5.2次对3.0次)。两组中MLB异常发现均很常见,但两组之间没有单一的MLB发现有显著差异。
NICU中胎龄≤30周、出生体重<1.5kg、患有严重肺部疾病且拔管尝试失败超过3次的早产儿更有可能需要气管切开术。