抗胸腺细胞血清、抗巨噬细胞血清和乳胶颗粒对同基因小鼠中卡介苗或液化棒状杆菌（痤疮丙酸杆菌C7）治疗效果的影响。
Effect of anti-thymocyte serum, anti-macrophage serum, and latex particles on the therapeutic efficacy of BCG or Corynebacterium liquefaciens (Propionibacterium acnes C7) in syngeneic mice.
作者信息
Tanaka T, Nakagawa H, Kato A, Yoshimura M, Fujita H, Kimura K
出版信息
Gan. 1977 Feb;68(1):45-52.
In a syngeneic mouse-tumor system, anti-thymocyte serum, anti-macrophage serum, and latex particles were used for a comparative study of the immunotherapeutic efficacy of intradermal inoculation of tumor cell-BCG and tumor cell-Corynebacterium liquefaciens (=Propionibacterium acnes C7) vaccines. Anti-thymocyte serum treatment nullified suppression of tumor mediated by BCG (living and nonliving) and living C. liquefaciens. However, the effect of nonliving C. liquefaciens was not affected so much by treatment with anti-thymocyte serum. Treatment with anti-macrophage serum or latex particles also imparied the therapeutic efficacy of living BCG, but had no influence on the efficacy of living and nonliving C. liquefaciens.
在同基因小鼠肿瘤系统中，使用抗胸腺细胞血清、抗巨噬细胞血清和乳胶颗粒，对肿瘤细胞 - 卡介苗和肿瘤细胞 - 液化棒状杆菌（=痤疮丙酸杆菌C7）疫苗皮内接种的免疫治疗效果进行比较研究。抗胸腺细胞血清处理消除了卡介苗（活的和灭活的）以及活的液化棒状杆菌介导的肿瘤抑制作用。然而，抗胸腺细胞血清处理对灭活的液化棒状杆菌的作用影响不大。抗巨噬细胞血清或乳胶颗粒处理也损害了活卡介苗的治疗效果，但对活的和灭活的液化棒状杆菌的效果没有影响。
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