Rashti Roya, Sharafi Heidar, Alavian Seyed Moayed, Moradi Yousef, Mohamadi Bolbanabad Amjad, Moradi Ghobad
Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj 6617713446, Iran.
Middle East Liver Diseases Center, Tehran 1598976513, Iran.
Pathogens. 2020 May 31;9(6):432. doi: 10.3390/pathogens9060432.
The main objective of this study was to evaluate the prevalence of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), hepatitis C virus (HCV) and hepatitis B virus (HBV) and their co-infections among people who inject drugs (PWID) and female sex workers (FSWs). Data sources were searched from January 2008 to October 2018 in different databases. Data were analyzed in Stata 16 software using the Metaprop command. The results showed that the prevalence of HIV, HCV and HBV among PWID was 15%, 60% and 6%, respectively. The prevalence of HIV, HCV and HBV among FSWs was 5%, 1% and 3%, respectively. The prevalence of HIV/HCV, HIV/HBV, HCV/HBV and HIV/HCV/HBV co-infections among PWID was 13%, 2%, 3% and 2%, respectively. The prevalence of HIV/HCV and HIV/HBV co-infections among FSWs was 3% and 1%, respectively. The results show that the prevalence of HCV and HIV infections in PWID and the prevalence of HIV in FSWs is higher than their prevalence in the general population. Interventions for the prevention of HIV and HCV in PWID appear to be poor, and may not be sufficient to effectively prevent HIV and HCV transmission.
本研究的主要目的是评估注射吸毒者（PWID）和女性性工作者（FSW）中人类免疫缺陷病毒/获得性免疫缺陷综合征（HIV/AIDS）、丙型肝炎病毒（HCV）和乙型肝炎病毒（HBV）的流行情况及其合并感染情况。于2008年1月至2018年10月在不同数据库中检索数据来源。使用Metaprop命令在Stata 16软件中对数据进行分析。结果显示，PWID中HIV、HCV和HBV的流行率分别为15%、60%和6%。FSW中HIV、HCV和HBV的流行率分别为5%、1%和3%。PWID中HIV/HCV、HIV/HBV、HCV/HBV和HIV/HCV/HBV合并感染的流行率分别为13%、2%、3%和2%。FSW中HIV/HCV和HIV/HBV合并感染的流行率分别为3%和1%。结果表明，PWID中HCV和HIV感染的流行率以及FSW中HIV的流行率高于其在普通人群中的流行率。针对PWID预防HIV和HCV的干预措施似乎效果不佳，可能不足以有效预防HIV和HCV传播。
