Coleman Megan, Akolo Christopher, Mbanusi Acapel, Sithole Bhekizitha, Siberry George K, Schowen Ryan, Goldstein Deborah
HIV Technical Advisor for Key Populations, Washington, DC, USA.
FHI 360, Washington, DC, USA.
J Int AIDS Soc. 2025 Sep;28(9):e70027. doi: 10.1002/jia2.70027.
Key populations (KP), including men who have sex with men, people who inject drugs, sex workers, transgender people and people in closed settings, are disproportionately affected by HIV and face structural and legal barriers to care. While community-led responses are central to reaching KP, services are often disease-specific and disconnected from national primary healthcare (PHC) systems. PHC, defined by WHO as a whole-of-society approach to delivering integrated and person-centred services, is rarely designed to meet the broader health needs of KP, who also experience high burdens of non-communicable diseases, mental health conditions and violence. This paper describes three service delivery models, supported by PEPFAR, that integrate HIV and PHC services for KP in Vietnam, Nigeria and Eswatini.
The three models are community-led, client-centred, and tailored to KP health and social needs. Each integrates HIV services-including testing, antiretroviral therapy, viral load monitoring, pre-exposure prophylaxis (PrEP) and advanced HIV disease management-alongside broader PHC services such as mental healthcare, sexual and reproductive health, non-communicable disease screening and tuberculosis services. All models include structural and community-based interventions such as gender-based violence support, stigma reduction, peer navigation and economic empowerment. These services are delivered in safe, trusted spaces by multidisciplinary teams including peer and clinical providers. While the models demonstrate alignment with PHC principles (accessibility, cultural competence, continuity and community empowerment), challenges remain related to integration within national health systems, financing and provider training. Recent U.S. global health policy shifts, including reductions in funding for KP-specific programming and limited PrEP access, pose additional threats to programme sustainability and client trust.
Integrated models of HIV and PHC for KP can improve access, engagement and health outcomes across a range of services. They represent promising approaches for addressing intersecting health and structural needs, particularly in settings where stigma and criminalization persist. Sustained progress will require inclusion of KP in PHC policies and planning, protection of community-led services and domestic financing strategies that ensure continuity in the face of shifting donor priorities.
重点人群,包括男男性行为者、注射吸毒者、性工作者、跨性别者以及封闭环境中的人群,受艾滋病毒影响的比例过高,并且在获得医疗服务方面面临结构性和法律障碍。虽然社区主导的应对措施对于覆盖重点人群至关重要,但服务往往针对特定疾病,且与国家初级卫生保健(PHC)系统脱节。世界卫生组织将初级卫生保健定义为一种全社会提供综合和以人为本服务的方法,但很少被设计用于满足重点人群更广泛的健康需求,这些人群还面临着非传染性疾病、心理健康问题和暴力的沉重负担。本文介绍了由美国总统艾滋病紧急救援计划(PEPFAR)支持的三种服务提供模式,这些模式将越南、尼日利亚和斯威士兰的重点人群的艾滋病毒和初级卫生保健服务整合在一起。
这三种模式由社区主导、以客户为中心,并根据重点人群的健康和社会需求进行量身定制。每种模式都将艾滋病毒服务——包括检测、抗逆转录病毒疗法、病毒载量监测、暴露前预防(PrEP)和晚期艾滋病毒疾病管理——与更广泛的初级卫生保健服务,如精神卫生保健、性健康和生殖健康、非传染性疾病筛查以及结核病服务整合在一起。所有模式都包括基于结构和社区的干预措施,如基于性别的暴力支持、减少耻辱感、同伴引导和经济赋权。这些服务由包括同伴和临床提供者在内的多学科团队在安全、可信赖的场所提供。虽然这些模式表明与初级卫生保健原则(可及性、文化能力、连续性和社区赋权)相一致,但在与国家卫生系统整合、融资和提供者培训方面仍存在挑战。美国最近的全球卫生政策转变,包括减少对针对重点人群项目的资金投入以及有限的暴露前预防药物获取机会,对项目的可持续性和客户信任构成了额外威胁。
针对重点人群的艾滋病毒和初级卫生保健综合模式可以改善一系列服务的可及性、参与度和健康结果。它们是解决交叉健康和结构需求的有前景的方法,特别是在耻辱感和定罪持续存在的环境中。持续取得进展将需要把重点人群纳入初级卫生保健政策和规划,保护社区主导的服务以及确保在面对不断变化的捐助方优先事项时保持连续性的国内融资战略。