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经直肠超声引导下前列腺动脉栓塞术治疗良性前列腺增生症:1000 余例治疗患者的俄罗斯多中心研究。

Prostatic Artery Embolization for Benign Prostatic Hyperplasia Treatment: A Russian Multicenter Study in More Than 1,000 Treated Patients.

机构信息

Urology and Andrology Department, Faculty of Medicine, Lomonosov Moscow State University, Moscow, Russia.

Urology Department, Moscow Research and Education Center of the Lomonosov Moscow State University, Moscow, Russia.

出版信息

Am J Mens Health. 2020 May-Jun;14(3):1557988320923910. doi: 10.1177/1557988320923910.

Abstract

Benign prostatic hyperplasia (BPH) is one of the most common diseases of the genitourinary system. The prevalence of BPH increases in men with advancing age. While transurethral resection of the prostate gland entails complications such as retrograde ejaculation, urinary incontinence, hematuria, urethral strictures, bladder neck sclerosis, and other adverse events, it is necessary to apply minimally invasive surgical methods such as superselective embolization of the prostatic arteries (PAE), particularly Proximal Embolization First Then Distal Embolization (PErFecTED). The data from 1,015 BPH patients who underwent endovascular surgery demonstrate the benefits of PErFecTED treatment during 24 months after surgery. Both Quality of Life score and International Prostate Symptom Score were around three times better in the PErFecTED group and remained stable during the entire observation period. However, the technique needs to be improved due to the high risk of postembolization syndrome.

摘要

良性前列腺增生症(BPH)是泌尿生殖系统最常见的疾病之一。BPH 的患病率随着男性年龄的增长而增加。虽然经尿道前列腺电切术会导致逆行射精、尿失禁、血尿、尿道狭窄、膀胱颈硬化等并发症,但有必要应用微创外科方法,如前列腺动脉超选择性栓塞(PAE),特别是近端栓塞先行远端栓塞(PErFecTED)。对 1015 例接受血管内手术的 BPH 患者的数据进行分析,结果表明,术后 24 个月内 PErFecTED 治疗具有优势。PErFecTED 组的生活质量评分和国际前列腺症状评分均提高了近 3 倍,且在整个观察期间保持稳定。然而,由于存在较高的栓塞后综合征风险,该技术仍需改进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33a2/7273342/36e69a356599/10.1177_1557988320923910-fig1.jpg

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