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荷兰人在为自己或孩子接种疫苗时的决策偏好差异:一项离散选择实验。

Preferential differences in vaccination decision-making for oneself or one's child in The Netherlands: a discrete choice experiment.

机构信息

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

BMC Public Health. 2020 Jun 1;20(1):828. doi: 10.1186/s12889-020-08844-w.

Abstract

BACKGROUND

To optimize the focus of future public information campaigns in The Netherlands promoting the uptake of vaccines among adults and children, we quantified the contribution of several attributes to the vaccination decision.

METHOD

We performed a discrete choice experiment (DCE) among Dutch adults including six attributes, i.e. vaccine effectiveness, vaccine-preventable burden of disease (specified in severity and frequency), accessibility of vaccination in terms of co-payment and prescription requirements, frequency of mild side-effects, population-level vaccination coverage and local vaccination coverage among family and friends. Participants answered the DCE from their own perspective ('oneself' group) or with regard to a vaccine decision for their youngest child ('child' group). The data was analysed by means of panel mixed logit models.

RESULTS

We included 1547 adult participants (825 'oneself' and 722 'child'). Vaccine effectiveness was the most important attribute in the 'oneself' group, followed by burden of disease (relative importance (RI) 78%) and accessibility (RI 76%). In the 'child' group, burden of disease was most important, but tied closely with vaccine effectiveness (RI 97%). Of less importance was the risk of mild vaccine-related side-effects and both population and local vaccination coverage. Interestingly, participants were more willing to vaccinate when uptake among the population or family and friends was high, indicating that social influence and social norms plays a role.

CONCLUSIONS

Vaccine effectiveness and disease severity are key attributes in vaccination decision-making for adults making a decision for themselves and for parents who decide for their children. Hence, public information campaigns for both adult and child vaccination should primarily focus on these two attributes. In addition, reinforcing social norms may be considered.

摘要

背景

为了优化未来荷兰推广成人和儿童疫苗接种的公共信息宣传活动的重点,我们量化了几个属性对疫苗接种决策的贡献。

方法

我们在荷兰成年人中进行了一项离散选择实验(DCE),其中包括六个属性,即疫苗效力、疫苗可预防疾病的负担(按严重程度和频率规定)、疫苗接种的可及性(包括共付费用和处方要求)、轻度副作用的频率、人群层面的疫苗接种覆盖率以及家庭和朋友中的当地疫苗接种覆盖率。参与者从自己的角度(“自己”组)或考虑为最小的孩子接种疫苗(“孩子”组)回答 DCE。通过面板混合对数模型分析数据。

结果

我们纳入了 1547 名成年参与者(825 名“自己”和 722 名“孩子”)。在“自己”组中,疫苗效力是最重要的属性,其次是疾病负担(相对重要性(RI)为 78%)和可及性(RI 为 76%)。在“孩子”组中,疾病负担最重要,但与疫苗效力密切相关(RI 为 97%)。轻度疫苗相关副作用的风险以及人群和当地疫苗接种覆盖率的重要性较低。有趣的是,当人群或家庭和朋友的接种率较高时,参与者更愿意接种疫苗,这表明社会影响和社会规范发挥了作用。

结论

疫苗效力和疾病严重程度是成年人自己做出决策和父母为孩子做出决策时疫苗接种决策的关键属性。因此,针对成人和儿童的疫苗接种的公共信息宣传活动应主要关注这两个属性。此外,可以考虑加强社会规范。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f194/7268356/2986a06c2a24/12889_2020_8844_Fig1_HTML.jpg

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