Department of Psychiatry, Saiseikai Central Hospital, Tokyo, Japan.
Department of Psychiatry, Ohizumi Hospital, Tokyo, Japan.
Neuropsychopharmacol Rep. 2020 Sep;40(3):232-238. doi: 10.1002/npr2.12118. Epub 2020 Jun 3.
Psychopharmacological treatment is indispensable in patients with schizophrenia but data on needs, preferences, and complaints about their medications are limited. Moreover, there has been no study to assess the degree of awareness of their psychiatrists (gap in needs) regarding these issues.
Ninety-seven Japanese patients with schizophrenia (ICD-10) were asked to fill in the questionnaire consisting of multiple-choice questions regarding (a) their needs and complaints about psychopharmacological treatment that they were receiving, and (b) their preference of dosage form, dosing frequency, and timing of dosing. Additionally, their psychiatrists in charge were asked to predict their patients' response to the above questions.
Both the most frequently endorsed need and complaints about the current psychopharmacological treatment were "nothing in particular" (n = 14, 16.7% and n = 17, 20.2%); merely 23.1% and 15.4% of their psychiatrists correctly predicted these responses, respectively. "Once a day" (n = 56, 65.1%), "at bedtime" (n = 53, 61.6%), and "tablet" (n = 51, 59.3%) were the patients' most favorite dosing frequency, timing, and dosage form, respectively; 59.8% (n = 49), 54.9% (n = 45), and 64.6% (n = 53) of their psychiatrists predicted them.
These findings suggest that there is substantial room for improvement on the side of psychiatrists to capture their patients' needs and complaints about psychopharmacological treatment.
精神分裂症患者的精神药理学治疗不可或缺,但有关其药物治疗需求、偏好和用药相关问题的资料有限。此外,目前尚无研究评估精神科医生对这些问题的认识程度(需求差距)。
97 例日本精神分裂症患者(ICD-10)填写了一份包含多项选择题的问卷,内容涉及他们正在接受的精神药理学治疗的需求和用药相关问题(a),以及他们对剂型、给药频率和给药时间的偏好(b)。此外,还要求他们的主管精神科医生预测患者对上述问题的反应。
目前精神药理学治疗中最常被认可的需求和用药相关问题都是“没什么特别的”(n=14,16.7%和 n=17,20.2%);仅有 23.1%和 15.4%的精神科医生正确预测了这些反应。“每天一次”(n=56,65.1%)、“睡前”(n=53,61.6%)和“片剂”(n=51,59.3%)是患者最喜爱的给药频率、时间和剂型,分别有 59.8%(n=49)、54.9%(n=45)和 64.6%(n=53)的精神科医生预测到了这些结果。
这些发现表明,精神科医生在了解患者对精神药理学治疗的需求和用药相关问题方面有很大的改进空间。