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潜在的免疫抑制?临床表现、发病机制、诊断检查及治疗。

: an underlying immunosuppression? Clinical manifestations, pathogenesis, diagnostic examinations and treatment.

作者信息

Nowak Marcela A, Putynkowska Anna, Barańska-Rybak Wioletta, Czarnacka Kamila, Dębska-Ślizień Maria A

机构信息

Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.

Department of Dermatology, Copernicus Hospital, Gdansk, Poland.

出版信息

Postepy Dermatol Alergol. 2020 Apr;37(2):154-158. doi: 10.5114/ada.2020.94833. Epub 2020 May 5.

DOI:10.5114/ada.2020.94833
PMID:32489347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7262803/
Abstract

Due to constantly growing population of immunocompromised patients the fungi became a widespread threat to modern medicine. HIV carriers, solid organ transplant recipients constitute most of those patients. Cryptococcosis is a frequent cause of life-threatening infections, affecting mostly immunosuppressed patients. This article presents current knowledge on cryptococcal infections, including epidemiology, clinical aspects, diagnosis and recommended treatment. In reference to our patient, who developed a disseminated and fulminant subtype of the disease, we wanted to underline the need to examine patients thoroughly. The highest aim of those measures would be to avoid lethal consequences.

摘要

由于免疫功能低下患者的数量不断增加,真菌已成为现代医学面临的广泛威胁。艾滋病毒携带者、实体器官移植受者构成了这些患者的大多数。隐球菌病是危及生命的感染的常见原因,主要影响免疫抑制患者。本文介绍了有关隐球菌感染的当前知识,包括流行病学、临床方面、诊断和推荐的治疗方法。针对我们的患者,他患上了该疾病的播散性暴发型亚型,我们想强调对患者进行全面检查的必要性。这些措施的最高目标是避免致命后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a2/7262803/ddadf325d48b/PDIA-37-40510-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a2/7262803/7a97c686c4ab/PDIA-37-40510-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a2/7262803/ddadf325d48b/PDIA-37-40510-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a2/7262803/7a97c686c4ab/PDIA-37-40510-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a2/7262803/ddadf325d48b/PDIA-37-40510-g002.jpg

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本文引用的文献

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Infect Dis Rep. 2015 Jun 3;7(2):5743. doi: 10.4081/idr.2015.5743. eCollection 2015 Apr 15.
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Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment. cryptococcosis:流行病学、真菌耐药性和新的治疗选择。
Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1377-91. doi: 10.1007/s10096-013-1915-8. Epub 2013 Jul 4.
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Cryptococcosis.
Cureus. 2024 Apr 11;16(4):e58040. doi: 10.7759/cureus.58040. eCollection 2024 Apr.
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Primary Cutaneous Cryptococcosis Caused by in an Elderly Patient.一名老年患者由新型隐球菌引起的原发性皮肤隐球菌病 。 你提供的原文“Primary Cutaneous Cryptococcosis Caused by in an Elderly Patient.”中“Caused by”后面似乎缺少具体病因内容,我按照完整语义进行了翻译,你可根据实际情况调整。
Trop Med Infect Dis. 2022 Aug 23;7(9):206. doi: 10.3390/tropicalmed7090206.
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Subcutaneous Mycoses in Travelers.旅行者的皮下真菌病
Curr Trop Med Rep. 2020 Dec;7(4):141-152. doi: 10.1007/s40475-020-00216-z. Epub 2020 Nov 6.
隐球菌病。
Clin Dermatol. 2012 Nov-Dec;30(6):599-609. doi: 10.1016/j.clindermatol.2012.01.005.
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Cutaneous cryptococcosis in a patient on chronic haemodialysis.
Nefrologia. 2012;32(5):697-8. doi: 10.3265/Nefrologia.pre2012.Jun.11563.
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Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.《隐球菌病治疗指南:美国传染病学会 2010 年更新版》
Clin Infect Dis. 2010 Feb 1;50(3):291-322. doi: 10.1086/649858.
6
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