Ondriska František, Boldiš Vojtech, Stanislavová Marta, Antolová Daniela, Miterpáková Martina, Hanáček Anton, Vešperová Soňa, Jančovič Ivan
Department of Laboratory Testing Methods in Health Care, Faculty of Health Care and Social Work, Trnava University, Trnava, Slovakia.
Department of Parasitology, Medirex (Ltd), Bratislava, Slovakia.
Iran J Parasitol. 2020 Jan-Mar;15(1):147-152.
is the causative agent of human subcutaneous or, less often, ocular dirofilariasis. The work presents a rare case of ocular dirofilariasis manifested by previous subcutaneous migration accompanied by severe headache symptoms. In February 2017, a 58-yr-old man from Trnava region, western Slovakia, noticed red and itchy stripes on his left leg. Inflamed but painless stripes disappeared and showed up again every 5-7 days, migrating gradually towards the head. Approximately one month after the first skin's alterations, strong pain in the left temple, with the swelling of the left face and the enlargement of mandibular lymph nodes appeared. Several days later, the patient felt excruciating pain of the right eyeball accompanied by strong nausea and subsequent vomiting. Ocular examination revealed the presence of a live worm in the subconjunctival space and morphological and molecular analyses of extracted helminth confirmed as etiological agent of the infection. According to clinical manifestation of the infection, it could be supposed that ocular form of the disease was the result of the migration of a parasite through the subcutaneous tissues. Moreover, a rare phenomenon of lymphadenitis of underlying lymph nodes and the swelling of left face accompanied the migration.
是人类皮下丝虫病的病原体，较少情况下也是眼部丝虫病的病原体。该研究报告了一例罕见的眼部丝虫病病例，此前有皮下迁移并伴有严重头痛症状。2017年2月，一名来自斯洛伐克西部特尔纳瓦地区的58岁男性注意到左腿上出现红色且瘙痒的条纹。发炎但无痛的条纹消失后，每隔5 - 7天又会出现，并逐渐向头部迁移。在首次皮肤出现改变大约一个月后，左侧太阳穴出现剧痛，同时左侧面部肿胀，下颌淋巴结肿大。几天后，患者感到右眼球剧痛，伴有强烈恶心及随后的呕吐。眼部检查发现结膜下空间有一条活虫，对提取的蠕虫进行形态学和分子分析证实其为感染的病原体。根据感染的临床表现，可以推测该疾病的眼部形式是寄生虫通过皮下组织迁移的结果。此外，在迁移过程中还出现了罕见的深部淋巴结炎和左侧面部肿胀现象。
