Harrogate Suzanne, Stretch Benjamin, Seatter Rosie, Finney Simon, Singer Ben
ACCS Anaesthetics CT1 Severn Deanery, Bristol, UK.
ACCS Anaesthetics CT1 Barts and the London School of Anaesthesia, London, UK.
J Intensive Care Soc. 2020 May;21(2):105-110. doi: 10.1177/1751143719848660. Epub 2019 May 9.
Extracorporeal cardiopulmonary resuscitation (ECPR) is an internationally recognised treatment for refractory cardiac arrest, with evidence of improved outcomes in selected patient groups from cohort studies and case series. In order to establish the clinical need for an in-hospital extracorporeal cardiopulmonary resuscitation service at a tertiary cardiac centre, we analysed the inpatient cardiac arrest database for the previous 12 months.
Evidence-based inclusion criteria were used to retrospectively identify the number of patients potentially eligible for extracorporeal cardiopulmonary resuscitation over a 12-month period.
A total of 261 inpatient cardiac arrests were analysed with 21 potential extracorporeal cardiopulmonary resuscitation candidates meeting the inclusion criteria (1.75 patients per month, or 8% of inpatient cardiac arrests (21/261)). The majority (71%) of these cardiac arrests occurred outside of normal working hours. Survival-to-discharge within this sub-group with conventional cardiopulmonary resuscitation was 19% (4/21).
Sufficient numbers of refractory inpatient cardiac arrests occur to justify an extracorporeal cardiopulmonary resuscitation service, but a 24-h on-site extracorporeal membrane oxygenation team presents a significant financial and logistical challenge.
体外心肺复苏(ECPR)是一种国际公认的治疗难治性心脏骤停的方法,队列研究和病例系列研究表明,特定患者群体采用该方法可改善预后。为确定一家三级心脏中心建立院内体外心肺复苏服务的临床必要性,我们分析了过去12个月的住院患者心脏骤停数据库。
采用循证纳入标准,回顾性确定12个月内可能符合体外心肺复苏条件的患者数量。
共分析了261例住院患者心脏骤停病例,其中21例潜在的体外心肺复苏候选者符合纳入标准(每月1.75例,占住院患者心脏骤停病例的8%(21/261))。这些心脏骤停事件大多(71%)发生在正常工作时间之外。该亚组患者经传统心肺复苏后的出院生存率为19%(4/21)。
难治性住院患者心脏骤停病例数量足以证明有必要开展体外心肺复苏服务,但组建一支24小时现场体外膜肺氧合团队面临重大的财务和后勤挑战。