与肠出血性大肠杆菌（EHEC）共同感染——一种潜在的致命组合。
co-infection with Enterohemorrhagic (EHEC)-a potentially fatal combination.
作者信息
Deshmukh Farah, Agrawal Upasana, Merrell Nancy
机构信息
Department of Internal Medicine, Bassett Medical Center and Columbia University College of Physicians and Surgeons, New York, USA.
Kasturba Medical College, Manipal, India.
出版信息
IDCases. 2020 May 8;21:e00797. doi: 10.1016/j.idcr.2020.e00797. eCollection 2020.
Abstract
There has been a significant increase in hospital and community acquired infection in the past decade. In addition to CDI, the rate of infection with enterohemorrhagic (EHEC) has also increased by 28% in United States in the last five years. Concomitant CDI and EHEC infections are rare and if not identified early such co-infections can be fatal. We present the case of patient with hematochezia who was found to be positive for and EHEC. She had a complicated hospital course that required timely identification of complications and management.
摘要
在过去十年中，医院获得性感染和社区获得性感染显著增加。除了艰难梭菌感染（CDI）外，美国肠出血性大肠杆菌（EHEC）感染率在过去五年中也上升了28%。CDI和EHEC合并感染很少见，如果不及早识别，这种合并感染可能是致命的。我们报告了一例便血患者，该患者被检测出EHEC呈阳性。她的住院过程很复杂，需要及时识别并发症并进行处理。
相似文献
1
co-infection with Enterohemorrhagic (EHEC)-a potentially fatal combination.与肠出血性大肠杆菌（EHEC）共同感染——一种潜在的致命组合。
IDCases. 2020 May 8;21:e00797. doi: 10.1016/j.idcr.2020.e00797. eCollection 2020.
2
Infection due to Shiga toxin-producing enterohemorrhagic (EHEC) presenting as ischemic colitis.由产志贺毒素的肠出血性大肠杆菌（EHEC）引起的感染，表现为缺血性结肠炎。
IDCases. 2019 Aug 22;18:e00629. doi: 10.1016/j.idcr.2019.e00629. eCollection 2019.
3
Probiotic Escherichia coli Nissle 1917 reduces growth, Shiga toxin expression, release and thus cytotoxicity of enterohemorrhagic Escherichia coli.益生菌大肠杆菌Nissle 1917可降低肠出血性大肠杆菌的生长、志贺毒素表达、释放，从而降低其细胞毒性。
Int J Med Microbiol. 2015 Jan;305(1):20-6. doi: 10.1016/j.ijmm.2014.10.003. Epub 2014 Oct 27.
4
Fatal Community-Acquired Clostridioides difficile Infection as a Cause of Listeria Meningitis: A Case Report.致命的社区获得性艰难梭菌感染作为李斯特菌性脑膜炎的病因：一例报告
Cureus. 2024 Feb 17;16(2):e54371. doi: 10.7759/cureus.54371. eCollection 2024 Feb.
5
Evaluation of real time PCR assays for the detection and enumeration of enterohemorrhagic Escherichia coli directly from cattle feces.用于直接从牛粪中检测和计数肠出血性大肠杆菌的实时聚合酶链反应检测方法的评估
J Microbiol Methods. 2014 Oct;105:72-9. doi: 10.1016/j.mimet.2014.07.015. Epub 2014 Jul 23.
6
Fatal case of hemolytic-uremic syndrome in an adult due to a rare serogroup O91 Entero hemorrhagic Escherichia coli associated with a Clostridium difficile infection. More than meets the eye.一名成人因罕见血清群O91肠出血性大肠杆菌感染并伴有艰难梭菌感染而导致溶血尿毒综合征死亡病例。不止表面这么简单。
Int J Infect Dis. 2015 Aug;37:113-4. doi: 10.1016/j.ijid.2015.06.015. Epub 2015 Jun 30.
7
The effect of probiotic treatment with Clostridium butyricum on enterohemorrhagic Escherichia coli O157:H7 infection in mice.丁酸梭菌益生菌治疗对小鼠肠出血性大肠杆菌O157:H7感染的影响。
FEMS Immunol Med Microbiol. 2004 Jul 1;41(3):219-26. doi: 10.1016/j.femsim.2004.03.010.
8
[Enterohemorrhagic Escherichia coli (EHEC) infection in infants and children].婴幼儿和儿童的肠出血性大肠杆菌（EHEC）感染
Nihon Rinsho. 2012 Aug;70(8):1338-42.
9
Community-acquired fulminant colitis caused by binary toxin-producing Clostridium difficile in Japan.日本由产二元毒素的艰难梭菌引起的社区获得性暴发性结肠炎。
Clin J Gastroenterol. 2019 Aug;12(4):325-329. doi: 10.1007/s12328-019-00949-z. Epub 2019 Feb 14.
10
[Enterohemorrhagic Escherichia coli and hemolytic-uremic syndrome].肠出血性大肠杆菌与溶血尿毒综合征
Wien Klin Wochenschr. 1997 Sep 19;109(17):669-77.
本文引用的文献
1
Atypical Haemolytic Uraemic Syndrome Associated with Infection Successfully Treated with Eculizumab.依库珠单抗成功治疗与感染相关的非典型溶血性尿毒症综合征。
Case Rep Nephrol. 2018 May 10;2018:1759138. doi: 10.1155/2018/1759138. eCollection 2018.
2
An unusual case of O157:H7 infection with pseudomembranous colitis-like lesions associated with haemolytic-uraemic syndrome and neurological sequelae.一例罕见的O157:H7感染病例，伴有类似假膜性结肠炎的病变，并与溶血尿毒综合征及神经后遗症相关。
BMJ Case Rep. 2017 Jun 18;2017:bcr-2016-218586. doi: 10.1136/bcr-2016-218586.
3
Fatal case of hemolytic-uremic syndrome in an adult due to a rare serogroup O91 Entero hemorrhagic Escherichia coli associated with a Clostridium difficile infection. More than meets the eye.一名成人因罕见血清群O91肠出血性大肠杆菌感染并伴有艰难梭菌感染而导致溶血尿毒综合征死亡病例。不止表面这么简单。
Int J Infect Dis. 2015 Aug;37:113-4. doi: 10.1016/j.ijid.2015.06.015. Epub 2015 Jun 30.
4
Burden of Clostridium difficile infection in the United States.美国艰难梭菌感染的负担
N Engl J Med. 2015 Jun 11;372(24):2369-70. doi: 10.1056/NEJMc1505190.
5
Clostridium difficile infection: management strategies for a difficult disease.艰难梭菌感染：一种难治疾病的管理策略
Therap Adv Gastroenterol. 2014 Mar;7(2):72-86. doi: 10.1177/1756283X13508519.
6
Hemolytic uremic syndrome and Clostridium difficile colitis.溶血性尿毒症综合征和艰难梭菌结肠炎。
J Community Hosp Intern Med Perspect. 2012 Oct 15;2(3). doi: 10.3402/jchimp.v2i3.19064. Print 2012.
7
Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals.志贺毒素与人类和动物溶血性尿毒症综合征的病理生理学。
Toxins (Basel). 2012 Nov 8;4(11):1261-87. doi: 10.3390/toxins4111261.
8
Characterization of cases of Clostridium difficile infection (CDI) presenting at an emergency room: molecular and clinical features differentiate community-onset hospital-associated and community-associated CDI in a tertiary care hospital.在一家三级医院中，急诊科就诊的艰难梭菌感染（CDI）病例的特征：分子和临床特征区分了社区获得性医院相关性和社区相关性 CDI。
J Clin Microbiol. 2011 Jun;49(6):2161-5. doi: 10.1128/JCM.02330-10. Epub 2011 Apr 6.
9
Fulminant, non-antibiotic associated Clostridium difficile colitis following Salmonella gastroenteritis.暴发性、非抗生素相关性艰难梭菌结肠炎继发于沙门氏菌胃肠炎。
J Gen Intern Med. 2011 Jan;26(1):95-7. doi: 10.1007/s11606-010-1466-y. Epub 2010 Aug 10.
10
Clostridium difficile after haemolytic uraemic syndrome.溶血尿毒综合征后的艰难梭菌感染
Arch Dis Child. 1993 Aug;69(2):239-40. doi: 10.1136/adc.69.2.239.
Zotero 插件