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Abdomen CT findings in a COVID-19 patient with intestinal symptoms and possibly false negative RT-PCR before initial discharge.

作者信息

Guo Yi, Hu Xiaofei, Yu Fei, Chen Jiao, Zheng Wei, Liu Jun, Zeng Ping

机构信息

Department of Radiology, Chongqing University Central Hospital, Chongqing 400014, China.

Department of Radiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.

出版信息

Quant Imaging Med Surg. 2020 May;10(5):1158-1161. doi: 10.21037/qims-20-463.

DOI:10.21037/qims-20-463
PMID:32489939
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7242287/
Abstract
摘要

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Abdomen CT findings in a COVID-19 patient with intestinal symptoms and possibly false negative RT-PCR before initial discharge.一名新冠肺炎患者在初始出院前出现肠道症状且逆转录聚合酶链反应(RT-PCR)可能为假阴性的腹部CT检查结果
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Two False Negative Test Results in a Symptomatic Patient with a Confirmed Case of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Suspected Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN).一名确诊感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)且疑似史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症(SJS/TEN)的有症状患者出现两次假阴性检测结果。
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Middle East J Dig Dis. 2022 Jul;14(3):278-286. doi: 10.34172/mejdd.2022.284. Epub 2022 Jul 30.
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Abdominal gastrointestinal imaging findings on computed tomography in patients with COVID-19 and correlation with clinical outcomes.COVID-19患者腹部胃肠道的计算机断层扫描成像结果及其与临床结局的相关性。
Eur J Radiol Open. 2021;8:100326. doi: 10.1016/j.ejro.2021.100326. Epub 2021 Jan 18.
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J Clin Med. 2020 Nov 11;9(11):3630. doi: 10.3390/jcm9113630.
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CT suggests discharged Covid-19 patients who were retested RT-PCR positive again for SARS-CoV-2 more likely had false negative RT-PCR tests before discharging.计算机断层扫描(CT)显示,新冠病毒疾病(Covid-19)康复出院患者中,再次进行逆转录聚合酶链反应(RT-PCR)检测结果呈严重急性呼吸综合征冠状病毒2(SARS-CoV-2)阳性的患者,在出院前的RT-PCR检测更有可能出现假阴性。
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本文引用的文献

1
Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes.轻度疾病严重程度的 COVID-19 患者的消化症状:临床表型、粪便病毒 RNA 检测和结局。
Am J Gastroenterol. 2020 Jun;115(6):916-923. doi: 10.14309/ajg.0000000000000664.
2
Gross examination report of a COVID-19 death autopsy.一份新冠死亡病例尸检大体检查报告。
Fa Yi Xue Za Zhi. 2020 Feb;36(1):21-23. doi: 10.12116/j.issn.1004-5619.2020.01.005. Epub 2020 Feb 25.
3
Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi: 10.1056/NEJMoa2002032. Epub 2020 Feb 28.
4
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.《武汉 2019 年新型冠状病毒感染的肺炎 138 例住院患者临床特征分析》
JAMA. 2020 Mar 17;323(11):1061-1069. doi: 10.1001/jama.2020.1585.
5
Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis.计算机断层扫描特征在鉴别肠结核与克罗恩病中的准确性:一项荟萃分析的系统评价
Intest Res. 2017 Apr;15(2):149-159. doi: 10.5217/ir.2017.15.2.149. Epub 2017 Apr 27.
6
Middle East respiratory syndrome.中东呼吸综合征
Lancet. 2015 Sep 5;386(9997):995-1007. doi: 10.1016/S0140-6736(15)60454-8. Epub 2015 Jun 3.
7
Exploring the pathogenesis of severe acute respiratory syndrome (SARS): the tissue distribution of the coronavirus (SARS-CoV) and its putative receptor, angiotensin-converting enzyme 2 (ACE2).探索严重急性呼吸综合征(SARS)的发病机制:冠状病毒(SARS-CoV)及其假定受体血管紧张素转换酶2(ACE2)的组织分布。
J Pathol. 2004 Jul;203(3):740-3. doi: 10.1002/path.1597.
8
Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways.严重急性呼吸综合征(SARS)相关冠状病毒(SARS-CoV)在SARS患者中的器官分布:对发病机制和病毒传播途径的影响。
J Pathol. 2004 Jun;203(2):622-30. doi: 10.1002/path.1560.
9
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.冠状病毒相关严重急性呼吸综合征肺炎社区暴发中的临床进展与病毒载量:一项前瞻性研究。
Lancet. 2003 May 24;361(9371):1767-72. doi: 10.1016/s0140-6736(03)13412-5.