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从日本腹泻驹分离鉴定到一株罕见的 A 群轮状病毒 G13P[18] 毒株。

Isolation and characterization of a rare group A rotavirus G13P[18] strain from a diarrhoeic foal in Japan.

机构信息

Equine Research Institute, Japan Racing Association, Shimotsuke, Tochigi, Japan.

Hokkaido South Agricultural Mutual Aid Association, Hidaka-cho, Hokkaido, Japan.

出版信息

J Gen Virol. 2020 Aug;101(8):800-805. doi: 10.1099/jgv.0.001437.

Abstract

A rare genotype G13P[18] group A rotavirus (RVA/Horse-tc/JPN/MK9/2019/G13P[18]) was isolated from a diarrhoeic foal for the first time in 28 years. The genotype constellation of the virus was assigned to G13-P[18]-I6-R9-C9-M6-A6-N9-T12-E14-H11 and was the same as that of the first isolated strain, RVA/Horse-tc/GBR/L338/1991/G13P[18]. Phylogenetic analysis suggests that the virus is related to RVA/Horse-tc/GBR/L338/1991/G13P[18] and is distant from typical equine rotaviruses of the G3P[12] and G14P[12] genotypes.

摘要

一株罕见的基因型 G13P[18]组 A 轮状病毒(RVA/Horse-tc/JPN/MK9/2019/G13P[18])于 28 年来首次从腹泻驹体中分离得到。该病毒的基因型组合被分配到 G13-P[18]-I6-R9-C9-M6-A6-N9-T12-E14-H11,与第一个分离株 RVA/Horse-tc/GBR/L338/1991/G13P[18]相同。系统进化分析表明,该病毒与 RVA/Horse-tc/GBR/L338/1991/G13P[18]相关,与典型的 G3P[12]和 G14P[12]基因型的马轮状病毒相距较远。

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