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胰腺脂肪变性:胃肠病学中的一种新诊断与治疗挑战

PANCREATIC STEATOSIS: A NEW DIAGNOSIS AND THERAPEUTIC CHALLENGE IN GASTROENTEROLOGY.

作者信息

Paul Jayanta, Shihaz Ambalathu Veettil Hussain

机构信息

Desun Hospital and Heart Institute, Department of Gastroenterology, Kolkata, India.

University Hospital of North Cumbria, Department of Gastroenterology, UK.

出版信息

Arq Gastroenterol. 2020 Apr-Jun;57(2):216-220. doi: 10.1590/s0004-2803.202000000-27.

Abstract

Fat infiltration in the pancreas is called pancreatic steatosis and it has several synonyms such as pancreatic lipomatosis, non-alcoholic fatty pancreatic disease, lipomatous pseudohypertrophy, fatty replacement, fatty pancreas and fatty infiltration. Pancreatic steatosis describes a disease ranging from infiltration of fat in the pancreas to pancreatic inflammation, and development of pancreatic fibrosis. There are multiple aetiologies of this condition, such as metabolic syndrome, alcohol intake, viral infections, toxins, congenital syndromes, etc. Pancreatic steatosis is usually diagnosed by trans-abdominal ultrasound, computed tomography scan and magnetic resonance imaging. Fatty infiltration in pancreas may lead to pancreatitis, diabetes mellitus and may be a predisposing cause of pancreatic cancer. Now a day, pancreatic steatosis is a common incidental finding during abdominal ultrasonography for other reasons and is a new challenge in Gastroenterology. But there is no guideline for pancreatic steatosis till now. In this review article, we are trying to give an overall idea (aetiologies, diagnosis, management, clinical significances) on pancreatic steatosis.

摘要

胰腺中的脂肪浸润被称为胰腺脂肪变性,它有几个同义词,如胰腺脂肪瘤病、非酒精性脂肪性胰腺疾病、脂肪性假性肥大、脂肪替代、脂肪胰腺和脂肪浸润。胰腺脂肪变性描述了一种从胰腺脂肪浸润到胰腺炎症以及胰腺纤维化发展的疾病。这种情况有多种病因,如代谢综合征、酒精摄入、病毒感染、毒素、先天性综合征等。胰腺脂肪变性通常通过经腹超声、计算机断层扫描和磁共振成像来诊断。胰腺脂肪浸润可能导致胰腺炎、糖尿病,并且可能是胰腺癌的一个诱发因素。如今,胰腺脂肪变性在因其他原因进行腹部超声检查时是一种常见的偶然发现,也是胃肠病学中的一个新挑战。但到目前为止还没有关于胰腺脂肪变性的指南。在这篇综述文章中,我们试图对胰腺脂肪变性给出一个总体概念(病因、诊断、管理、临床意义)。

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