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地塞米松玻璃体内植入物在晶状体中的应用:一例报告

Dexamethasone intravitreal implant in the crystalline lens: a case report.

作者信息

Ertan Elif, Duman Reşat, Duman Rahmi, Doğan Mustafa

机构信息

Department of Ophthalmology, Siirt Kurtalan State Hospital, Siirt, Turkey.

Department of Ophthalmology, School of Medicine, Afyon University of Health Sciences, Afyonkarahisar, Turkey.

出版信息

Arq Bras Oftalmol. 2020 Jun;83(3):242-245. doi: 10.5935/0004-2749.20200065. Epub 2020 May 29.

DOI:10.5935/0004-2749.20200065
PMID:32490981
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11826655/
Abstract

This report describes the therapeutic effects and outcomes of an accidental injection of an intralenticular sustained-release dexamethasone implant (Ozurdex®) in three patients with diabetic macular edema. All three patients underwent accidental injections of sustained-release intravitreal dexamethasone implants into the crystalline lens by the same surgeon. After the accidental injection of Ozurdex® into the crystalline lens, a remarkable reduction in the macular edema and an improvement in visual acuity were observed, suggesting that a positive outcome can be achieved without immediate surgery.

摘要

本报告描述了3例糖尿病性黄斑水肿患者意外眼内注射长效地塞米松植入剂(Ozurdex®)的治疗效果及预后。所有3例患者均由同一位外科医生意外将长效玻璃体内地塞米松植入剂注射入晶状体。意外将Ozurdex®注射入晶状体后,观察到黄斑水肿明显减轻,视力提高,提示无需立即手术即可取得良好预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/80a85df0920c/abo-83-03-0242-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/dde600c17a0f/abo-83-03-0242-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/128bd8ae7d45/abo-83-03-0242-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/80a85df0920c/abo-83-03-0242-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/dde600c17a0f/abo-83-03-0242-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/128bd8ae7d45/abo-83-03-0242-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e84/11826655/80a85df0920c/abo-83-03-0242-g03.jpg

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Int Med Case Rep J. 2025 Jan 7;18:27-32. doi: 10.2147/IMCRJ.S486866. eCollection 2025.

本文引用的文献

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Intralenticular Sustained-Release Dexamethasone Implant: Is It Still Effective on Macular Edema?晶状体囊内缓释地塞米松植入物:对黄斑水肿是否仍有效?
Case Rep Ophthalmol. 2016 Feb 12;7(1):85-9. doi: 10.1159/000444163. eCollection 2016 Jan-Apr.
2
Accidental intralenticular dexamethasone intravitreal implant with the resolution of macular oedema in central retinal vein occlusion.意外眼内晶状体地塞米松玻璃体内植入与中心性视网膜静脉阻塞黄斑水肿的消退
Acta Ophthalmol. 2016 Dec;94(8):e810-e811. doi: 10.1111/aos.13062. Epub 2016 Apr 29.
3
Accidental insertion of dexamethasone implant into the crystalline lens--12 months follow-up.
地塞米松植入物意外植入晶状体——12个月随访
Eye (Lond). 2014 May;28(5):624-5. doi: 10.1038/eye.2014.18. Epub 2014 Feb 21.
4
Inadvertent dexamethasone implant injection into the lens body management.晶状体体内意外注射地塞米松植入物的处理
Eur J Ophthalmol. 2014 Jul-Aug;24(4):620-2. doi: 10.5301/ejo.5000436. Epub 2014 Feb 3.
5
Accidental injection of dexamethasone intravitreal implant in the crystalline lens.地塞米松玻璃体内植入剂意外注射入晶状体。
Acta Ophthalmol. 2014 Jun;92(4):e330-1. doi: 10.1111/aos.12332. Epub 2013 Dec 24.
6
Repositioning and follow-up of intralenticular dexamethasone implant.晶状体内曲安奈德植入物的重新定位和随访。
J Cataract Refract Surg. 2013 Aug;39(8):1271-4. doi: 10.1016/j.jcrs.2013.06.003.
7
[Reliability and safety of intravitreal Ozurdex injections. The ZERO study].[玻璃体内注射Ozurdex的可靠性和安全性。ZERO研究]
Ophthalmologe. 2014 Jan;111(1):44-52. doi: 10.1007/s00347-012-2737-2.
8
Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion.随机、假手术对照试验研究地塞米松眼内植入剂治疗视网膜静脉阻塞所致黄斑水肿患者。
Ophthalmology. 2010 Jun;117(6):1134-1146.e3. doi: 10.1016/j.ophtha.2010.03.032. Epub 2010 Apr 24.