Celis Diego, Gomes Bruno Alvares de Azevedo, Ibanez Ivan, Azevedo Pedro Nieckele, Teixeira Pedro Soares, Nieckele Angela Ourivio
Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio) - Departamento de Engenharia Mecânica, Rio de Janeiro, RJ - Brasil.
Instituto Nacional de Cardiologia, Ministério da Saúde, Rio de Janeiro, RJ - Brasil.
Arq Bras Cardiol. 2020 Oct;115(4):680-687. doi: 10.36660/abc.20190385.
Transcatheter aortic valve replacement (TAVR) can reduce mortality among patients with aortic stenosis. Knowledge of pressure distribution and shear stress at the aortic wall may help identify critical regions, where aortic remodeling process may occur. Here a numerical simulation study of the influence of positioning of the prosthetic valve orifice on the flow field is presented.
The present analysis provides a perspective of great variance on flow behavior due only to angle changes.
A 3D model was generated from computed tomography angiography of a patient who had undergone a TAVR. Different mass flow rates were imposed at the inlet valve.
Small variations of the tilt angle could modify the nature of the flow, displacing the position of the vortices, and altering the prerssure distribution and the location of high wall shear stress.
These hemodynamic features may be relevant in the aortic remodeling process and distribution of the stress mapping and could help, in the near future, the optimization of the percutaneous prosthesis implantation. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).
经导管主动脉瓣置换术(TAVR)可降低主动脉瓣狭窄患者的死亡率。了解主动脉壁的压力分布和剪切应力可能有助于识别可能发生主动脉重塑过程的关键区域。本文展示了一项关于人工瓣膜孔位置对血流场影响的数值模拟研究。
本分析仅从角度变化方面提供了血流行为的巨大差异视角。
根据一名接受TAVR患者的计算机断层血管造影生成三维模型。在入口瓣膜处施加不同的质量流率。
倾斜角度的微小变化可能会改变血流性质,改变涡流位置,改变压力分布以及高壁面剪切应力的位置。
这些血流动力学特征可能与主动脉重塑过程及应力映射分布相关,并可能在不久的将来有助于优化经皮假体植入。(《巴西心脏病学杂志》。2020年;[在线]。预印本,第0 - 0页)