Baig Muhammad U., Bodle Jeffrey
Quaid-e-Azam Medical College
Atrium Health
Thrombolytics or fibrinolytic are a group of medications used to manage and treat dissolving intravascular clots. They are in the plasminogen activator class of drugs. This class of medicine is used in acute myocardial infarction, deep vein thrombosis, pulmonary embolism, acute ischemic stroke, acute peripheral arterial occlusion, occlusion of indwelling catheters, and intracardiac thrombus formation. This activity describes the indications, action, and contraindications for thrombolytics. This activity will also highlight the mechanism of action, adverse event profile, monitoring, and toxicity pertinent for interprofessional team members in treating patients with intravascular clots such as acute myocardial infarction, acute ischemic stroke, and related conditions.
溶栓剂或纤维蛋白溶解剂是一类用于处理和治疗血管内血栓溶解的药物。它们属于纤溶酶原激活剂类药物。这类药物用于急性心肌梗死、深静脉血栓形成、肺栓塞、急性缺血性中风、急性外周动脉闭塞、留置导管闭塞以及心内血栓形成。本活动描述了溶栓剂的适应症、作用和禁忌症。本活动还将重点介绍作用机制、不良事件概况、监测以及对于治疗血管内血栓患者（如急性心肌梗死、急性缺血性中风及相关病症）的跨专业团队成员而言相关的毒性。
