Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Department of Orthopedic Surgery, Regional Hospital Horsens, Horsens, Denmark.
PLoS One. 2020 Jun 3;15(6):e0234041. doi: 10.1371/journal.pone.0234041. eCollection 2020.
One-year mortality after hip-fracture is a widely used outcome measure when comparing hospital care performance. However, traditional analyses do not explicitly consider the referral of patients to municipality care after just a few days of hospitalization. Furthermore, traditional analyses investigates hospital (or municipality) variation in patient outcomes in isolation rather than as a component of the underlying patient variation. We therefore aimed to extend the traditional approach to simultaneously estimate both case-mix adjusted hospital and municipality comparisons in order to disentangle the amount of the total patient variation in clinical outcomes that was attributable to the hospital and municipality level, respectively.
We determined 1-year mortality risk in patients aged 65 or above with hip fractures registered in Sweden between 2011 and 2014. We performed cross-classified multilevel analysis with 54,999 patients nested within 54 hospitals and 290 municipalities. We adjusted for individual demographic, socioeconomic and clinical characteristics. To quantify the size of the hospital and municipality variation we calculated the variance partition coefficient (VPC) and the area under the receiver operator characteristic curve (AUC).
The overall 1-year mortality rate was 25.1%. The case-mix adjusted rates varied from 21.7% to 26.5% for the 54 hospitals, and from 18.9% to 29.5% for the 290 municipalities. The VPC was just 0.2% for the hospital and just 0.1% for the municipality level. Patient sociodemographic and clinical characteristics were strong predictors of 1-year mortality (AUC = 0.716), but adding the hospital and municipality levels in the cross-classified model had a minor influence (AUC = 0.718).
Overall in Sweden, one-year mortality after hip-fracture is rather high. However, only a minor part of the patient variation is explained by the hospital and municipality levels. Therefore, a possible intervention should be nation-wide rather than directed to specific hospitals or municipalities.
髋部骨折后一年的死亡率是比较医院护理绩效时广泛使用的结果衡量指标。然而,传统分析并未明确考虑患者在住院几天后转往市政护理的情况。此外,传统分析孤立地研究医院(或市政当局)的患者结果差异,而不是作为患者差异的组成部分。因此,我们旨在扩展传统方法,同时估计病例组合调整后的医院和市政当局的比较,以厘清临床结果总患者差异中归因于医院和市政当局水平的部分。
我们确定了 2011 年至 2014 年间在瑞典登记的年龄在 65 岁及以上的髋部骨折患者的 1 年死亡率风险。我们对 54999 名患者进行了交叉分类多水平分析,这些患者嵌套在 54 家医院和 290 个市政当局中。我们对个体人口统计学、社会经济和临床特征进行了调整。为了量化医院和市政当局差异的大小,我们计算了方差分量系数(VPC)和接收者操作特征曲线下的面积(AUC)。
总体 1 年死亡率为 25.1%。病例组合调整后的比率在 54 家医院中从 21.7%到 26.5%不等,在 290 个市政当局中从 18.9%到 29.5%不等。医院水平的 VPC 仅为 0.2%,市政当局水平的 VPC 仅为 0.1%。患者社会人口统计学和临床特征是 1 年死亡率的强有力预测因素(AUC = 0.716),但在交叉分类模型中加入医院和市政当局水平的影响较小(AUC = 0.718)。
在瑞典,髋部骨折后一年的死亡率总体较高。然而,只有一小部分患者差异可以通过医院和市政当局的水平来解释。因此,可能的干预措施应该是全国性的,而不是针对特定的医院或市政当局。