Matta Mario, Gaita Fiorenzo, Anselmino Matteo
Division of Cardiology, Department of Medical Sciences, "Città della Salute e della Scienza" Hospital, University of Turin, Italy.
J Innov Card Rhythm Manag. 2017 Mar 15;8(3):2648-2656. doi: 10.19102/icrm.2017.080304. eCollection 2017 Mar.
Catheter ablation of atrial fibrillation (AF) is a widely recommended treatment for patients presenting with symptomatic AF refractory to pharmacological treatment. AF ablation is also becoming a therapeutic option for patients with chronic heart failure (CHF), on top of optimal medical treatment, as AF is related to a higher risk of death, the worsening of symptoms, and the progression of CHF in this patient cohort. The present systematic review describes all published experiences concerning the use of AF catheter ablation among CHF patients and/or patients with structural cardiomyopathies, in an effort to summarize procedural safety and efficacy in this specific setting. Moreover, the effects of AF ablation on functional class and quality of life, as well as the different procedural protocols available, are presented and discussed, aiming to provide an evidence-based clinical perspective to optimize indication and tailor procedural characteristics and endpoints to patients affected by CHF referred for AF ablation.
导管消融治疗心房颤动(AF)是一种广泛推荐用于药物治疗无效的症状性AF患者的治疗方法。除了最佳药物治疗外,AF消融也正成为慢性心力衰竭(CHF)患者的一种治疗选择,因为在这一患者群体中,AF与更高的死亡风险、症状恶化以及CHF进展相关。本系统评价描述了所有已发表的关于在CHF患者和/或结构性心肌病患者中使用AF导管消融的经验,旨在总结这一特定情况下的手术安全性和有效性。此外,还介绍并讨论了AF消融对心功能分级和生活质量的影响,以及可用的不同手术方案,旨在提供基于证据的临床观点,以优化适应证,并根据接受AF消融的CHF患者的情况调整手术特点和终点。