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职业性获得性耐甲氧西林金黄色葡萄球菌定植与职业性皮肤病评估(德国职业病列表中的BK-No. 3101):对德国社会保险协会(DGUV)文件的分析以及关于一例与工作相关的耐甲氧西林金黄色葡萄球菌引发的特应性皮炎病例的专家意见

[Occupationally acquired MRSA colonization and occupational dermatological assessments (BK-No. 3101 in the German list of Occupational Diseases) : Analysis of the DGUV documentation and expert opinion on a case with work-related MRSA-triggered atopic dermatitis].

作者信息

Erfurt-Berge Cornelia, Schmidt Anne, Angelovska Irena, Mahler Vera

机构信息

Hautklinik Universitätsklinikum Erlangen, Erlangen, Deutschland.

Büro für Berufsdermatologie, Begutachtung und Betriebsberatung, Nürnberg, Deutschland.

出版信息

Hautarzt. 2020 Aug;71(8):613-623. doi: 10.1007/s00105-020-04616-0.

DOI:10.1007/s00105-020-04616-0
PMID:32494841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7268186/
Abstract

BACKGROUND

Person-to-person transmitted infectious diseases can cause occupational diseases (OD). These are subsumed as BK-No. 3101 in the German list of OD which applies for individuals with a considerably higher risk for infection as a consequence of their professional activity compared to the general population.

OBJECTIVES

The special medical and insurance law aspects of a work-related MRSA colonization are presented using the example of an expert opinion case and an evaluation of the BK reports of suspected occupational disease (BK No. 3101) of the German Social Accident Insurance (DGUV).

PATIENTS AND METHODS

The BK documentation of the DGUV from 2007-2012 and the patient cohort from the Department of Dermatology, University Hospital Erlangen, presenting for expert assessment from 2007-2012 were retrospectively analysed for human-to-human transmitted infectious diseases of the skin (BK-No. 3101).

RESULTS

Person-to-person transmission of infectious diseases of the skin is rare in the field of occupational dermatology. In the DGUV cohort, suspected BK-No. 3101cases amounted to 2.6% of all notified cases; recognized BK-No. 3101 cases accounted for 4.2% of all recognized cases, amongst which 9 were caused by MRSA. In contrast to a symptomatic infection, an asymptomatic MRSA colonization is not being recognized as BK-No. 3101. Bacterial superantigens can trigger atopic dermatitis (AD). In particular cases, occupationally acquired MRSA can elicit AD and may justify classification as an OD (BK-No. 3101).

CONCLUSIONS

Early detection of MRSA colonization and eradication are necessary for rehabilitation. Management of skin diseases due to infectious diseases within the framework of OD is presented.

摘要

背景

人际传播的传染病可导致职业病。在德国职业病列表中,这些被归类为BK-No.3101,适用于因职业活动而比普通人群感染风险高得多的个体。

目的

以一个专家意见案例以及对德国社会事故保险(DGUV)疑似职业病(BK No.3101)的BK报告评估为例,介绍与工作相关的耐甲氧西林金黄色葡萄球菌(MRSA)定植的特殊医疗和保险法律方面。

患者与方法

对2007 - 2012年DGUV的BK文档以及2007 - 2012年在埃尔朗根大学医院皮肤科就诊以进行专家评估的患者队列进行回顾性分析,以研究皮肤的人际传播传染病(BK-No.3101)。

结果

在职业皮肤病领域,皮肤传染病的人际传播很少见。在DGUV队列中,疑似BK-No.3101病例占所有报告病例的2.6%;确诊的BK-No.3101病例占所有确诊病例的4.2%,其中9例由MRSA引起。与有症状感染不同,无症状的MRSA定植未被认定为BK-No.3101。细菌超抗原可引发特应性皮炎(AD)。在特定情况下,职业获得性MRSA可引发AD,并可能证明可归类为职业病(BK-No.3101)。

结论

早期检测和根除MRSA定植对于康复是必要的。介绍了在职业病框架内对传染病所致皮肤病的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4c/7268186/2628c2c83a59/105_2020_4616_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4c/7268186/489a5736633d/105_2020_4616_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4c/7268186/2628c2c83a59/105_2020_4616_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4c/7268186/489a5736633d/105_2020_4616_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c4c/7268186/2628c2c83a59/105_2020_4616_Fig2_HTML.jpg

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Methicillin-resistant Staphylococcus aureus colonization and disease severity in atopic dermatitis: a cross-sectional study from South India.耐甲氧西林金黄色葡萄球菌定植与特应性皮炎疾病严重程度的关系:来自印度南部的横断面研究。
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