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阴道分娩产妇及围产结局的比较:有指征地引产与自发临产。

A comparison of maternal and perinatal outcomes with vaginal delivery: indicated induction versus spontaneous labor.

机构信息

Department of Obstetrics and Gynecology, University of Arkansas for the Medical Sciences, Little Rock, AR, USA.

Department of Biostatistics, University of Arkansas for the Medical Sciences, Little Rock, AR, USA.

出版信息

J Matern Fetal Neonatal Med. 2022 May;35(10):1929-1934. doi: 10.1080/14767058.2020.1774545. Epub 2020 Jun 4.

Abstract

OBJECTIVE

To determine if there is a difference in the maternal and perinatal characteristics and outcomes of women undergoing a medically indicated labor induction and delivering vaginally compared to women in spontaneous labor delivering vaginally.

METHODS

This is a planned secondary analysis of previously published data with additional data collected for a case-control design. Maternal and perinatal characteristics and outcomes of women undergoing a medically indicated labor induction of labor and delivering vaginally were compared with the next woman who went into labor spontaneously and delivered vaginally.

RESULTS

There were 1097 women in the medically indicated labor group and 1096 women in the spontaneous labor group. The medically indicated induction group was younger ( < .0001), had less women of "other" race ( = .004), were of a lower gravidity and parity ( < .0001), had a lower Bishops' score on admission ( < .0001), had a greater proportion of umbilical arterial cord pH values <7.1 and <7.0 ( < .0001). Additionally, the induction group had longer first and second stages of labor ( < .0001). While the unadjusted rates of post-partum complications and NICU admission were higher in the medically indicated labor induction group, only cord gas pH <7.1 remained statistically significant after adjustment.

CONCLUSION

Even with successful vaginal delivery of a medically indicated induction of labor, the risk for adverse outcomes remains elevated.

摘要

目的

确定与自发性分娩的阴道分娩相比,因医学指征行引产并阴道分娩的产妇和围产儿特征及结局是否存在差异。

方法

这是对先前发表的数据进行的计划二次分析,并为病例对照设计收集了额外的数据。将因医学指征行引产并阴道分娩的产妇和围产儿特征及结局与下一位自发性阴道分娩的产妇进行比较。

结果

因医学指征行引产的产妇有 1097 例,自发性分娩的产妇有 1096 例。因医学指征行引产的产妇年龄更小( < .0001),“其他”种族的产妇比例更少( = .004),孕次和产次更低( < .0001),入院时的 Bishop 评分更低( < .0001),脐动脉血 pH 值<7.1 和<7.0 的比例更高( < .0001)。此外,引产组的第一产程和第二产程均较长( < .0001)。虽然因医学指征行引产组的产后并发症和新生儿重症监护病房(NICU)入住率较高,但调整后只有脐带血 pH 值<7.1 仍具有统计学意义。

结论

即使成功进行了因医学指征行引产的阴道分娩,不良结局的风险仍然较高。

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