Department of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Primary and Secondary Healthcare Department, Government of Punjab (CEO (DHA) office D.G.Khan), Dera Ghazi Khan, Pakistan.
Rev Med Virol. 2020 Jul;30(4):e2116. doi: 10.1002/rmv.2116. Epub 2020 Jun 4.
In late December 2019, a group of patients was observed with pneumonia-like symptoms that were linked with a wet market in Wuhan, China. The patients were found to have a novel coronavirus genetically related to a bat coronavirus that was termed SARS-CoV-2. The virus gradually spread worldwide and was declared a pandemic by WHO. Scientists have started trials on potential preventive and treatment options. Currently, there is no specific approved treatment for SARS-CoV-2, and various clinical trials are underway to explore better treatments. Some previously approved antiviral and other drugs have shown some in vitro activity. Here we summarize the fight against this novel coronavirus with particular focus on the different treatment options and clinical trials exploring treatment as well as work done toward development of vaccines.
2019 年 12 月下旬，观察到一组具有肺炎样症状的患者，这些患者与中国武汉的一个湿市场有关。研究人员发现，这些患者携带的新型冠状病毒与一种蝙蝠冠状病毒在基因上有关，被称为 SARS-CoV-2。该病毒逐渐在全球范围内传播，并被世界卫生组织宣布为大流行。科学家们已经开始对潜在的预防和治疗方法进行试验。目前，尚无针对 SARS-CoV-2 的特定批准治疗方法，正在进行各种临床试验以探索更好的治疗方法。一些先前批准的抗病毒和其他药物已显示出一些体外活性。在这里，我们特别关注不同的治疗选择和临床试验，总结了对抗这种新型冠状病毒的努力，以探索治疗方法以及疫苗开发工作。
