Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
Org Lett. 2020 Jun 19;22(12):4878-4882. doi: 10.1021/acs.orglett.0c01722. Epub 2020 Jun 4.
A tricationic cage was synthesized via click chemistry. The cage has a preorganized cavity, which is surrounded by six relatively acidic C-H bonds. In organic solvent, the cage can recognize a variety of anions, among which the Cl anion has the highest binding affinity due to size selectivity. The cage is also able to selectively recognize the Cl anion in water, even though the binding affinity is just moderate.
通过点击化学合成了一种三阳离子笼。该笼具有预组织的空腔，被六个相对酸性的 C-H 键包围。在有机溶剂中，该笼可以识别多种阴离子，其中 Cl 阴离子由于尺寸选择性而具有最高的结合亲和力。该笼还能够在水中选择性地识别 Cl 阴离子，尽管结合亲和力只是中等。
