Khatri Deepak, Wagner Katherine, Ligas Barbara, Higbie Catherine, Langer David
Department of Neurosurgery, Lenox Hill Hospital, New York, New York.
Oper Neurosurg (Hagerstown). 2020 Sep 15;19(4):E411. doi: 10.1093/ons/opaa130.
Retrochiasmatic craniopharyngiomas are difficult to treat due to their close proximity to critical neurovascular structures. Several surgical approaches with distinct advantages and limitations have been described to access these tumors, including extended transnasal endoscopic approach (ETEA), subtemporal, translamina terminalis, and transpetrosal approach.1-3 We present a 51-yr-old male with a large retrochiasmatic craniopharyngioma extending into the third ventricle, causing obstructive hydrocephalus. Preoperative magnetic resonance imaging (MRI) showed a tumor cyst abutting the fornices expanding the space between two internal cerebral veins (ICV). After surgical consent, we decided to take advantage of this corridor to approach the tumor in its long axis. Surgical goal was to achieve cyst decompression with "safe maximal" resection of the solid component at last to preserve the pituitary function. Though the long axis of the tumor could be approached using ETEA, we preferred this approach in view of cyst decompression early in the surgery while completely avoiding risks such as cerebrospinal fluid (CSF) rhinorrhea, internal carotid artery (ICA) injury, and sinonasal complications. We utilized a 3-dimensional 4 K exoscope, which provides an excellent ergonomic position, and a high-resolution immersive view compared to a microscope or endoscope. Cyst decompression and near-total resection of the solid component was achieved. Postoperatively, his headaches improved and he was neurologically intact with intact neuroendocrine function. Approach-related risks may include but not limited to hemorrhage due to the rupture of venous sinuses or ICV, stalk or hypothalamus injury, and memory disturbances due to forniceal injury. To conclude, the transcallosal, interforniceal approach to retrochiasmatic craniopharyngiomas may provide a safe surgical corridor in select cases. Patient consented to the proposed procedure. All radiological images have been anonymized. IRB/ethics committee approval was not required.
视交叉后颅咽管瘤因其紧邻关键神经血管结构而难以治疗。为了切除这些肿瘤,已描述了几种具有不同优缺点的手术入路,包括扩大经鼻内镜入路(ETEA)、颞下、经终板和经岩骨入路。1-3我们报告了一名51岁男性,患有巨大的视交叉后颅咽管瘤,肿瘤延伸至第三脑室,导致梗阻性脑积水。术前磁共振成像(MRI)显示一个肿瘤囊肿紧邻穹窿,扩大了大脑内静脉(ICV)之间的间隙。在获得手术同意后,我们决定利用这个通道沿肿瘤长轴接近肿瘤。手术目标是实现囊肿减压,最终对实性部分进行“安全最大化”切除,以保留垂体功能。尽管可以使用ETEA接近肿瘤的长轴,但考虑到在手术早期进行囊肿减压,同时完全避免脑脊液(CSF)鼻漏、颈内动脉(ICA)损伤和鼻窦并发症等风险,我们更倾向于这种入路。我们使用了三维4K外视镜,与显微镜或内镜相比,它提供了极佳的人体工程学位置和高分辨率沉浸式视野。实现了囊肿减压和实性部分的近全切除。术后,他的头痛症状改善,神经功能完好,神经内分泌功能正常。与入路相关的风险可能包括但不限于静脉窦或ICV破裂导致的出血、柄或下丘脑损伤以及穹窿损伤导致的记忆障碍。总之,经胼胝体、经穹窿入路治疗视交叉后颅咽管瘤在某些情况下可能提供一个安全的手术通道。患者同意了拟议的手术。所有放射影像均已匿名化处理。无需获得机构审查委员会/伦理委员会批准。