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Neonatal early-onset sepsis calculator recommended significantly less empiric antibiotic treatment than national guidelines.新生儿早发型败血症计算器推荐的经验性抗生素治疗显著少于国家指南。
Acta Paediatr. 2020 Dec;109(12):2549-2551. doi: 10.1111/apa.15391. Epub 2020 Jun 17.
2
A sepsis risk calculator can decrease antibiotic exposure in neonatal early-onset sepsis screening.脓毒症风险计算器可减少新生儿早发型脓毒症筛查中的抗生素暴露。
Acta Paediatr. 2020 Oct;109(10):2166-2167. doi: 10.1111/apa.15332. Epub 2020 May 26.
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Implementation of the Neonatal Sepsis Calculator in Early-Onset Sepsis and Maternal Chorioamnionitis.新生儿脓毒症计算器在早发型脓毒症和产妇绒毛膜羊膜炎中的应用
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Neonatal Early-Onset Sepsis Calculator and Antibiotic Therapy.
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5
Neonatal Early-Onset Sepsis Calculator and Antibiotic Therapy.
JAMA Pediatr. 2020 May 1;174(5):508. doi: 10.1001/jamapediatrics.2019.6260.
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Neonatal Early-Onset Sepsis Calculator and Antibiotic Therapy-Reply.
JAMA Pediatr. 2020 May 1;174(5):508-509. doi: 10.1001/jamapediatrics.2019.6269.
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Impact of neonatal early-onset sepsis calculator on antibiotic use within two tertiary healthcare centers.新生儿早发型败血症计算器对两个三级医疗中心抗生素使用的影响。
J Perinatol. 2017 Apr;37(4):394-397. doi: 10.1038/jp.2016.236. Epub 2016 Dec 22.
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Comparison of the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with NICE guideline CG149 in infants ≥34 weeks' gestation who developed early-onset sepsis.比较 Kaiser Permanente 新生儿早发性败血症风险计算器（SRC）与 NICE 指南 CG149 在 ≥34 周胎龄发生早发性败血症的婴儿中的管理建议。
Arch Dis Child Fetal Neonatal Ed. 2020 Nov;105(6):581-586. doi: 10.1136/archdischild-2019-317165. Epub 2020 Mar 13.
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Comparison of institutional guidelines with established early onset sepsis risk calculator in reducing antibiotic use in an inner-city NICU in US.比较机构指南与既定的早发性败血症风险计算器，以减少美国市中心 NICU 中的抗生素使用。
J Glob Antimicrob Resist. 2020 Jun;21:124-129. doi: 10.1016/j.jgar.2020.03.015. Epub 2020 Mar 29.
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Application of sepsis calculator in newborns with suspected infection.脓毒症计算器在疑似感染新生儿中的应用。
J Matern Fetal Neonatal Med. 2016 Dec;29(23):3860-5. doi: 10.3109/14767058.2016.1149563. Epub 2016 Mar 7.

引用本文的文献

1
Safety and effectiveness of the early-onset sepsis calculator to reduce antibiotic exposure in at-risk newborns: a cluster-randomised controlled trial.早期败血症计算器在降低高危新生儿抗生素暴露方面的安全性和有效性：一项整群随机对照试验。
EClinicalMedicine. 2025 Aug 12;87:103419. doi: 10.1016/j.eclinm.2025.103419. eCollection 2025 Sep.
2
Diagnosis and Management of Neonatal Bacterial Sepsis: Current Challenges and Future Perspectives.新生儿细菌性败血症的诊断与管理：当前挑战与未来展望
Trop Med Infect Dis. 2024 Aug 28;9(9):199. doi: 10.3390/tropicalmed9090199.
3
Bacteriological profile and antibiotic susceptibility pattern of septicemia in neonatal intensive care units in Palestine: A retrospective study.巴勒斯坦新生儿重症监护病房败血症的细菌学特征及抗生素敏感性模式：一项回顾性研究。
IJID Reg. 2023 Dec 1;10:87-93. doi: 10.1016/j.ijregi.2023.11.019. eCollection 2024 Mar.
4
The Management of Neonates ≥34 Weeks' Gestation at Risk of Early Onset Sepsis: A Pilot Study.孕龄≥34周有早发型败血症风险的新生儿的管理：一项初步研究。
Antibiotics (Basel). 2023 Aug 10;12(8):1306. doi: 10.3390/antibiotics12081306.
5
Umbilical Cord Procalcitonin to Detect Early-Onset Sepsis in Newborns: A Promising Biomarker.脐血降钙素原用于检测新生儿早发型败血症：一种有前景的生物标志物。
Front Pediatr. 2021 Dec 10;9:779663. doi: 10.3389/fped.2021.779663. eCollection 2021.
6
Early-onset sepsis risk calculator: a review of its effectiveness and comparative study with our evidence-based local guidelines.早发型脓毒症风险计算器：有效性评价及其与本地区循证指南的比较研究。
Ital J Pediatr. 2021 Mar 25;47(1):73. doi: 10.1186/s13052-021-01028-1.
7
Time to Positivity of Blood Cultures Could Inform Decisions on Antibiotics Administration in Neonatal Early-Onset Sepsis.血培养转阴时间可为新生儿早发型败血症抗生素使用决策提供依据。
Antibiotics (Basel). 2021 Jan 28;10(2):123. doi: 10.3390/antibiotics10020123.

本文引用的文献

1
Multicentre study found that adherence to national antibiotic recommendations for neonatal early-onset sepsis was low.多中心研究发现，新生儿早发性败血症的国家抗生素推荐用药的遵从率较低。
Acta Paediatr. 2021 Mar;110(3):791-798. doi: 10.1111/apa.15488. Epub 2020 Aug 10.
2
Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns.早期败血症计算器的应用与晚期早产儿和足月儿医疗资源利用及财务成本的降低相关。
Eur J Pediatr. 2020 May;179(5):727-734. doi: 10.1007/s00431-019-03510-9. Epub 2020 Jan 2.
3
Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety: A Systematic Review and Meta-analysis.新生儿早发型败血症计算器的使用与抗生素治疗减少及安全性的关联：一项系统评价和荟萃分析
JAMA Pediatr. 2019 Nov 1;173(11):1032-1040. doi: 10.1001/jamapediatrics.2019.2825.
4
Screening for early onset neonatal sepsis: NICE guidance-based practice versus projected application of the Kaiser Permanente sepsis risk calculator in the UK population.早发型新生儿败血症筛查：基于 NICE 指南的实践与 Kaiser Permanente 败血症风险计算器在英国人群中的预计应用比较。
Arch Dis Child Fetal Neonatal Ed. 2020 Mar;105(2):118-122. doi: 10.1136/archdischild-2018-316777. Epub 2019 Jul 11.
5
Stratification of risk of early-onset sepsis in newborns ≥ 34 weeks' gestation.≥34 周胎龄新生儿早发性脓毒症风险分层。
Pediatrics. 2014 Jan;133(1):30-6. doi: 10.1542/peds.2013-1689. Epub 2013 Dec 23.

Neonatal early-onset sepsis calculator recommended significantly less empiric antibiotic treatment than national guidelines.

作者信息

van der Weijden Bo M, Achten Niek B, Bekhof Jolita, Evers Esther E, van Dongen Oviedo, Rijpert Maarten, Kamps Arvid W A, Ten Tusscher Gavin W, van Houten Marlies A, Plötz Frans B

机构信息

Department of Paediatrics, Tergooi Hospital, Blaricum, The Netherlands.

Department of Paediatrics, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands.

出版信息

Acta Paediatr. 2020 Dec;109(12):2549-2551. doi: 10.1111/apa.15391. Epub 2020 Jun 17.

DOI:10.1111/apa.15391
PMID:32497338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7754364/
Abstract
摘要