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酸化亚氯酸钠溶液:一种减轻一线医护人员多次接触新冠病毒影响的潜在预防措施。

Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers.

作者信息

Karnik-Henry Meghana S

机构信息

Scientific Affairs, Lundbeck , Deerfield, IL, USA.

出版信息

Hosp Pract (1995). 2020 Oct;48(4):165-168. doi: 10.1080/21548331.2020.1778908. Epub 2020 Jun 25.

Abstract

Limited availability of personal protective equipment is endangering first-line health-care providers treating patients with presumed or confirmed COVID-19 infections. This editorial has multiple objectives in regard to this reality: First, to raise awareness of the need for safe and effective prophylaxis to protect health-care providers with insufficient personal protective equipment from repeated exposures to COVID-19. Second, to summarize the scientific evidence in support of solutions of acidified sodium chlorite (ASC) and its daughter compounds, chlorous acid and chlorine dioxide, as potential targets for said prophylactic use. Third, to propose a regimented protocol using commercially available solutions of ASC having sufficient concentrations of chlorine dioxide for virucidal activity to support safe and effective prophylactic use. And fourth, to raise awareness of and compare other potential prophylactic options currently under investigation.

摘要

个人防护装备供应有限,正危及治疗疑似或确诊感染新冠病毒患者的一线医护人员。针对这一现实情况,本社论有多个目标:第一,提高人们对安全有效预防措施必要性的认识,以保护个人防护装备不足的医护人员避免反复接触新冠病毒。第二,总结支持亚氯酸钠酸化溶液(ASC)及其衍生化合物(氯酸和二氧化氯)作为上述预防性用途潜在目标的科学证据。第三,提出一种规范方案,使用具有足够二氧化氯浓度以实现杀病毒活性的市售ASC溶液,以支持安全有效的预防性使用。第四,提高人们对目前正在研究的其他潜在预防选项的认识并进行比较。

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本文引用的文献

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Characterization of Virucidal Activities of Chlorous Acid.氯酸的杀病毒活性表征
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Efficacy and Safety Evaluation of a Chlorine Dioxide Solution.二氧化氯溶液的疗效与安全性评估
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