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Outcomes of relapsed or refractory acute myeloid leukemia after frontline hypomethylating agent and venetoclax regimens.

作者信息

Maiti Abhishek, Rausch Caitlin R, Cortes Jorge E, Pemmaraju Naveen, Daver Naval G, Ravandi Farhad, Garcia-Manero Guillermo, Borthakur Gautam, Naqvi Kiran, Ohanian Maro, Short Nicholas J, Alvarado Yesid, Kadia Tapan M, Takahashi Koichi, Yilmaz Musa, Jain Nitin, Kornblau Steven, Montalban Bravo Guillermo, Sasaki Koji, Andreeff Michael, Bose Prithiviraj, Ferrajoli Alessandra, Issa Ghayas C, Jabbour Elias J, Masarova Lucia, Thompson Philip A, Wang Sa, Konoplev Sergej, Pierce Sherry A, Ning Jing, Qiao Wei, Welch John S, Kantarjian Hagop M, DiNardo Courtney D, Konopleva Marina Y

机构信息

Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, USA.

Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston, USA.

出版信息

Haematologica. 2021 Mar 1;106(3):894-898. doi: 10.3324/haematol.2020.252569.

DOI:10.3324/haematol.2020.252569
PMID:32499238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7927994/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b3d/7927994/5de11d84b561/106894.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b3d/7927994/33600b4e4224/106894.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b3d/7927994/5de11d84b561/106894.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b3d/7927994/33600b4e4224/106894.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b3d/7927994/5de11d84b561/106894.fig2.jpg

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Blood. 2020 Mar 12;135(11):791-803. doi: 10.1182/blood.2019003988.
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Nat Rev Cancer. 2019 Nov;19(11):611-624. doi: 10.1038/s41568-019-0196-7. Epub 2019 Sep 11.
3
Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies.
Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML.
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