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轻度至中度帕金森病患者的过渡性运动任务

Transitional Locomotor Tasks in People With Mild to Moderate Parkinson's Disease.

作者信息

Kamieniarz Anna, Michalska Justyna, Marszałek Wojciech, Akbaş Anna, Słomka Kajetan J, Krzak-Kubica Agnieszka, Rudzińska-Bar Monika, Juras Grzegorz

机构信息

Institute of Sport Sciences, Academy of Physical Education, Katowice, Poland.

Department of Neurology, Medical University of Silesia in Katowice, University Clinical Center, Katowice, Poland.

出版信息

Front Neurol. 2020 May 15;11:405. doi: 10.3389/fneur.2020.00405. eCollection 2020.

Abstract

People with Parkinson's disease (PD) exhibit deficits in maintaining balance both during quiet standing and during walking, turning, standing up from sitting, and step initiation. The purpose of this study was to examine balance disorders during a transitional task under different conditions in participants with PD. The research was conducted on 15 PD-II (mild) and 15 PD-III (moderate) individuals (H&Y II-III stage) and 30 healthy elderly. The transitional task was measured on two force platforms (A and B). The procedure consisted of three phases: (1) quiet standing on platform A, (2) crossing to platform B, and (3) quiet standing on platform B, each until measurements were completed. There were four conditions: crossing without an obstacle, crossing with an obstacle, and walking up and down the step. There were no significant differences between mild PD individuals and healthy elderly during quiet standing before the transitional task and after completing the task. The temporal aspects describing the different transitional tasks were comparable between mild PD and healthy subjects. Moderate PD participants presented a significantly higher COP velocity after the transitional task compared to the healthy older adults ( < 0.05). Additionally, the moderate PD group showed significantly higher values for transit time relative to healthy subjects during the transitional task in all conditions ( < 0.05). Disease severity affects the temporal aspects of different transitional tasks in people with PD. The procedure of completing a transitional task under different conditions allowed differences between moderate and mild PD stages and healthy subjects to be observed.

摘要

帕金森病(PD)患者在安静站立、行走、转身、从坐姿站起以及起步时均表现出平衡能力缺陷。本研究旨在考察帕金森病患者在不同条件下的过渡任务期间的平衡障碍。研究对象为15名PD-II(轻度)和15名PD-III(中度)个体(H&Y II-III期)以及30名健康老年人。过渡任务在两个测力平台(A和B)上进行测量。该过程包括三个阶段:(1)在平台A上安静站立,(2)穿过平台A到平台B,(3)在平台B上安静站立,每个阶段持续到测量完成。共有四种条件:无障碍穿过、有障碍穿过以及上下台阶行走。在过渡任务前的安静站立期间以及任务完成后,轻度帕金森病个体与健康老年人之间无显著差异。描述不同过渡任务的时间参数在轻度帕金森病患者与健康受试者之间具有可比性。与健康老年人相比,中度帕金森病参与者在过渡任务后表现出显著更高的COP速度(<0.05)。此外,在所有条件下的过渡任务期间,中度帕金森病组相对于健康受试者的过渡时间值显著更高(<0.05)。疾病严重程度会影响帕金森病患者不同过渡任务的时间参数。在不同条件下完成过渡任务的过程使得能够观察到中度与轻度帕金森病阶段以及健康受试者之间的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0142/7242736/52e6f5c1b836/fneur-11-00405-g0001.jpg

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