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腹腔镜袖状胃切除术治疗肥胖2型糖尿病患者的疗效:系统评价与Meta分析方案

Efficacy of laparoscopic sleeve gastrectomy in obese patients with type 2 diabetes mellitus: A protocol of systematic review and meta-analysis.

作者信息

Wei Wei-Wei, Fu Xian-Dong, Su De-Wang, Ke De-Zhi, Yao Rong-Rong, Chen Ke-Yan, Tian Hao

机构信息

Department of General Surgery.

Department of Interventional Radiology.

出版信息

Medicine (Baltimore). 2020 Jun 5;99(23):e20535. doi: 10.1097/MD.0000000000020535.

Abstract

BACKGROUND

A numerous studies have reported that obese patients (OP) are easily to have type 2 diabetes mellitus (T2DM). Although a variety of managements are available to treat such disorder, their efficacy is still limited. Previous studies have reported that laparoscopic sleeve gastrectomy (LSGT) can benefit OP with T2DM. However, no study specifically and systematically explores this topic. Thus, this study will assess the efficacy and complications of LSGT for the management of OP with T2DM.

METHODS

The search strategy will be performed in the electronic databases from inception to the March 31, 2020 without limitations of language and publication time: PUBMED, EMBASE, Cochrane Library, Scopus, Web of Science, CINAHL, AMED, WANGFANG, VIP, and CNKI. Two authors will independently identify the articles, collect the data, and assess the risk of bias using Cochrane risk of bias tool. We will invite a third author to solve any differences between two authors. We will use RevMan 5.3 software to investigate the statistical analysis.

RESULTS

This study will supply a high-quality synthesis of randomized controlled trials (RCTs) on the analysis of LSGT for the management of OP with T2DM.

CONCLUSIONS

This study will help to build proposals that aim at providing high quality RCTs in the management of LSGT in OP with T2DM.

SYSTEMATIC REVIEW REGISTRATION

INPLASY202040128.

摘要

背景

大量研究报告称肥胖患者(OP)易患2型糖尿病(T2DM)。尽管有多种治疗方法可用于治疗这种疾病,但其疗效仍然有限。先前的研究报告称,腹腔镜袖状胃切除术(LSGT)对患有T2DM的OP有益。然而,尚无研究专门且系统地探讨这一主题。因此,本研究将评估LSGT治疗患有T2DM的OP的疗效和并发症。

方法

检索策略将在从数据库建立到2020年3月31日的电子数据库中进行,不受语言和发表时间的限制:PUBMED、EMBASE、Cochrane图书馆、Scopus、科学网、CINAHL、AMED、万方、维普和知网。两位作者将独立识别文章、收集数据,并使用Cochrane偏倚风险工具评估偏倚风险。我们将邀请第三位作者解决两位作者之间的任何分歧。我们将使用RevMan 5.3软件进行统计分析。

结果

本研究将提供关于LSGT治疗患有T2DM的OP的高质量随机对照试验(RCT)综合分析。

结论

本研究将有助于制定旨在为患有T2DM的OP进行LSGT治疗提供高质量RCT的建议。

系统评价注册

INPLASY202040128。

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