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正常人体内可交换钠:不同参考框架的分析

Exchangeable body sodium in normal man: analysis of various frames of reference.

作者信息

de Châtel R, Tislér A, Herendi M, Barna I, Tóth M, Krasznai I

机构信息

First Department of Medicine, Semmelweis University Medical School, Budapest, Hungary.

出版信息

Acta Physiol Hung. 1988;72(3-4):359-66.

PMID:3250214
Abstract

Exchangeable sodium is a reliable measure of body sodium contents. Since fat tissue contains significantly less sodium per unit of weight than other tissues, leanness of an individual may considerably affect exchangeable body sodium. Thus, subjects of different body size can be compared only when body build is considered. To evaluate various frames of reference, we analysed the relationship between exchangeable sodium as determined by isotope dilution and various parameters of body size. Body weight, body height, body surface area, and leanness index correlated significantly with exchangeable sodium, the closest relationship having been obtained with body surface area (r = 0.790; p less than 0.001). When analysing males and females separately (n = 18 and 36, resp.), best parallelism of regression lines was also obtained with body surface area. It is concluded that exchangeable sodium should be referred to unit of body surface area, expressing each individual's value as percent of the normal predicted value calculated from the regression equations y = 1388x + 370 and y = 1554x - 196 for males and females, respectively.

摘要

可交换钠是身体钠含量的可靠指标。由于脂肪组织每单位重量所含的钠比其他组织少得多,个体的瘦胖程度可能会显著影响身体可交换钠的含量。因此,只有在考虑体型的情况下,才能对不同体型的受试者进行比较。为了评估各种参考标准,我们分析了通过同位素稀释法测定的可交换钠与各种体型参数之间的关系。体重、身高、体表面积和瘦度指数与可交换钠显著相关,其中与体表面积的关系最为密切(r = 0.790;p < 0.001)。当分别分析男性和女性(分别为n = 18和36)时,同样与体表面积获得了最佳的回归线平行度。得出的结论是,可交换钠应以体表面积单位来表示,将每个个体的值表示为分别根据回归方程y = 1388x + 370(男性)和y = 1554x - 196(女性)计算出的正常预测值的百分比。

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