Ali Sief, Okasha Ahmed, Elsirgany Sherif, Abdel-Rasheed Mazen, Khalil Ahmed, El-Anwary Sherif, Elsheikhah Ahmad
Department of Obstetrics & Gynecology, Assiut University, Egypt.
Reproductive Health Research Department, National Research Centre, Egypt.
Eur J Obstet Gynecol Reprod Biol. 2020 Aug;251:66-72. doi: 10.1016/j.ejogrb.2020.05.011. Epub 2020 May 21.
To develop gestational age-based reference ranges for the modified Doppler myocardial performance index (Mod MPI) and to examine the maternal characteristics that affect this measurement.
This was a cross-sectional study, comprised of 1021 healthy pregnancies between 20+0 to 35+6 weeks' gestation. They were all undergoing ultrasound examination in Cairo Fetal Medicine Unit (CAIFM) in Cairo University, Egypt from 1st April 2017 till 1st April 2019. Mod MPI was obtained used method described by Friedman et al. (2003). Median and SD models were fitted between Mod MPI and gestational age. The distributions of Mod MPI Z-scores were examined in relation to maternal characteristics RESULTS: The normal Mod MPI in second and third trimester (20 + 1 to 35 + 6 weeks' gestation) was 0.408 ± 0.08. Mod MPI was not affected by maternal age, body mass index (BMI) or parity (p value 0.5, 0.6 and 0.2 respectively).
This study established normal reference ranges for Mod MPI according to gestational age and generated a graph with 5th,10th, 90th and 95th centiles. Maternal characteristics as age, BMI or parity do not affect value of Mod MPI.
建立基于孕周的改良多普勒心肌性能指数（Mod MPI）参考范围，并研究影响该测量值的母体特征。
这是一项横断面研究，纳入了1021例孕20⁺⁰至35⁺⁶周的健康孕妇。她们于2017年4月1日至2019年4月1日期间在埃及开罗大学开罗胎儿医学科（CAIFM）接受超声检查。采用Friedman等人（2003年）描述的方法获得Mod MPI。对Mod MPI与孕周进行中位数和标准差模型拟合。根据母体特征检查Mod MPI Z评分的分布情况。结果：孕中期和晚期（孕20⁺¹至35⁺⁶周）的正常Mod MPI为0.408±0.08。Mod MPI不受产妇年龄、体重指数（BMI）或产次的影响（p值分别为0.5、0.6和0.2）。
本研究根据孕周建立了Mod MPI的正常参考范围，并生成了包含第5、第10、第90和第95百分位数的图表。产妇年龄、BMI或产次等母体特征不影响Mod MPI值。
