Department of Obstetrics and Gynecology, College of Medicine, Pan African University Life and Earth Sciences Institutes, University of Ibadan, Ibadan, Nigeria.
Department of Environmental Health, Faculty of Public Health, University of Ibadan, Ibadan, Oyo State, Nigeria.
Int J Gynaecol Obstet. 2020 Sep;150(3):361-367. doi: 10.1002/ijgo.13259. Epub 2020 Jun 25.
To determine the association between oil pollution and miscarriage, stillbirth, and infant death in the Niger Delta region of Nigeria.
A retrospective cohort study was undertaken of pregnant women (aged 18-45 years) who attended selected health facilities in regions with high and low exposure to oil pollution from May 14, 2018, to September 27, 2018. A multistage sampling technique was used to randomly select a representative of women with high and low exposure to oil pollution. An interviewer-administered questionnaire was used for data collection. Bivariate and multivariable logistic regression analyses were employed to adjust for confounding factors of miscarriage, stillbirth, and infant death.
In total, 1564 pregnant women were included in the study. Women with high exposure to oil pollution were more likely to experience stillbirth (odds ratio [OR] 1.806; 95% confidence interval [CI] 1.177-2.770) and infant death (OR 2.162; 95% CI 1.409-3.317). However, after adjusting for potential confounders, only infant death was associated with high exposure (adjusted OR 1.843; 95% CI 1.146-2.962). No association was found between miscarriage and high exposure to oil pollution.
Women with high exposure to oil pollution are at higher risk of infant death.
确定尼日利亚尼日尔三角洲地区的石油污染与流产、死产和婴儿死亡之间的关联。
这是一项回顾性队列研究，研究对象为 2018 年 5 月 14 日至 9 月 27 日期间在高、低石油污染暴露地区就诊的 18-45 岁孕妇。采用多阶段抽样技术随机选择高、低石油污染暴露孕妇的代表。采用访谈者管理的问卷收集数据。采用双变量和多变量逻辑回归分析调整流产、死产和婴儿死亡的混杂因素。
共纳入 1564 名孕妇。高石油污染暴露的孕妇更有可能发生死产（比值比 [OR] 1.806；95%置信区间 [CI] 1.177-2.770）和婴儿死亡（OR 2.162；95% CI 1.409-3.317）。然而，在调整潜在混杂因素后，只有婴儿死亡与高暴露相关（调整后的 OR 1.843；95% CI 1.146-2.962）。高暴露与流产之间没有关联。
高暴露于石油污染的孕妇婴儿死亡风险更高。
