HEPIDA-Ca和HEPIDA-Zn复合化合物的抗炎和免疫抑制活性。
The antiinflammatory and immunosuppressive activity of HEPIDA-Ca and HEPIDA-Zn complex compounds.
作者信息
Samochocka K, Ryzewski J, Kossakowska M
机构信息
Department of Chemistry, University of Warsaw.
出版信息
Arch Immunol Ther Exp (Warsz). 1988;36(3):377-80.
PMID:3250359
Abstract
The authors investigated the immunological and pharmacological activity of N-/2, 4-dimethylacetanilido/iminodiacetic complex compounds with calcium and zinc (HEPIDA-Ca and HEPIDA-Zn). An antiinflammatory, therapeutic effect of these compounds and also an immunosuppressive action were observed. Both complex compounds inhibited the GvH reaction in rats and attenuated the transplantation barrier.
摘要
作者研究了N-/2,4-二甲基乙酰苯胺基/亚氨基二乙酸与钙和锌的络合物（HEPIDA-Ca和HEPIDA-Zn）的免疫和药理活性。观察到这些化合物具有抗炎、治疗作用以及免疫抑制作用。两种络合物均抑制大鼠的移植物抗宿主反应并减弱移植屏障。
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