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心肌梗死后患者的心脏机械能量学:从与心肌耗氧量相关的压力-容积环图。

Cardiac Mechanoenergetics in Patients with Acute Myocardial Infarction: From Pressure-Volume Loop Diagram Related to Cardiac Oxygen Consumption.

机构信息

University of Texas Southwestern Medical Center, Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, 7232 Greenville Avenue, Dallas, TX 75231, USA.

Yoka Municipal Hospital, 1187-1 Yoka, Yabu-City, Hyogo 667-8555, Japan.

出版信息

Heart Fail Clin. 2020 Jul;16(3):255-269. doi: 10.1016/j.hfc.2020.02.002.

DOI:10.1016/j.hfc.2020.02.002
PMID:32503750
Abstract

Acute myocardial infarction (AMI) results in significant changes in cardiac structure and functions, leading to left ventricular remodeling and subsequent systolic and diastolic dysfunction. To improve current approaches in diagnoses, treatments, and prevention of cardiovascular diseases, a better understanding of cardiac mechanoenergetics, including systolic performance and energy demand, becomes paramount. In this review, we summarize cardiac mechanics, cardiac energetics, and their relationship in complications related to AMI using 2 important physiologic frameworks, pressure-volume loops and the Vo-pressure-volume area relationship diagram, as they are powerful tools for understanding physiologic behavior and mechanoenergetics of the left ventricle.

摘要

急性心肌梗死(AMI)导致心脏结构和功能发生重大变化,导致左心室重构以及随后的收缩和舒张功能障碍。为了改善心血管疾病的诊断、治疗和预防现状,更好地理解心脏力学,包括收缩性能和能量需求,变得至关重要。在这篇综述中,我们使用 2 个重要的生理框架,即压力-容积环和 Vo-压力-容积面积关系图,总结了与 AMI 相关并发症中的心脏力学、心脏能量学及其关系,因为它们是理解左心室生理行为和力学的有力工具。

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Cardiac Mechanoenergetics in Patients with Acute Myocardial Infarction: From Pressure-Volume Loop Diagram Related to Cardiac Oxygen Consumption.心肌梗死后患者的心脏机械能量学:从与心肌耗氧量相关的压力-容积环图。
Heart Fail Clin. 2020 Jul;16(3):255-269. doi: 10.1016/j.hfc.2020.02.002.
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Left ventricular mechanoenergetics in small animals.小动物的左心室机械能量学
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Linear O2 use-pressure-volume area relation from curved end-systolic pressure-volume relation of the blood-perfused rat left ventricle.从血液灌注的大鼠左心室的曲线性收缩末期压力-容积关系得出的线性氧耗-压力-容积面积关系。
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Crossbridge model compatible with the linear relation between left ventricular oxygen consumption and pressure-volume area.与左心室氧耗量和压力-容积面积之间线性关系相符的横桥模型。
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