Division of Digestive Surgery (Gastric Surgery Division), Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kawaramachi-hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Department of Surgery (Gastric Surgery Division), Kyoto First Red Cross Hospital, 15-749 Honmachi, Higashiyama-ku, Kyoto, 605-0981, Japan.
Langenbecks Arch Surg. 2020 Jun;405(4):541-549. doi: 10.1007/s00423-020-01900-4. Epub 2020 Jun 5.
No ideal and generally accepted method of reconstruction for laparoscopic proximal gastrectomy (LPG) has been established because of a high incidence of postoperative reflux and anastomotic stenosis. The aim of this study was to evaluate the short-term outcomes of LPG with a non-flap hand-sewn technique as a simple anti-reflux procedure for the upper part of clinical Stage I gastric cancer.
Between November 2016 and June 2019, 23 consecutive gastric cancer patients, who underwent curative LPG with lymphadenectomy, were enrolled in the study. In this study, we devised a simple hand-sewn technique for esophagogastrostomy, which comprises a 5-cm pseudo-fornix as a fundoplication, the posterior pressure mechanism by the remnant stomach and bilateral crus, and a flat-shaped anastomotic hole as a valvuloplasty.
The median operation time and hospital stay was 325 min and 10 days, respectively. There was no patient with anastomotic leakage and delayed gastric empting. No patient had symptoms of gastroesophageal reflux, but two patients (8.6% (2/23): Grade M and Grade A) had endoscopic findings during a follow-up period of more than 6 months. There was no patient with Grade B or more severe reflux esophagitis. One patient (4.3%, 1/23) developed anastomotic stenosis, which was resolved with endoscopic dilatation. The mean body weight loss at 6 months after surgery was 7.5% in comparison with the preoperative body weight.
Our non-flap hand-sewn technique for esophagogastrostomy had favorable outcomes and might be one of reliable techniques as an anti-reflux procedure in LPG for gastric cancer.
由于腹腔镜近端胃切除术(LPG)后反流和吻合口狭窄的发生率较高,因此尚未建立理想且被普遍接受的重建方法。本研究旨在评估 LPG 联合非瓣手缝技术治疗临床Ⅰ期胃癌上部的短期疗效,该技术作为一种简单的抗反流术式。
2016 年 11 月至 2019 年 6 月,连续 23 例接受根治性 LPG 及淋巴结清扫术的胃癌患者入组本研究。本研究设计了一种简单的食管胃吻合手缝技术,包括 5cm 假穹窿作为胃底折叠术、残胃和双侧胃底皱襞的后向压力机制以及平坦型吻合口作为瓣成形术。
中位手术时间和住院时间分别为 325 分钟和 10 天。无吻合口漏和胃排空延迟发生。无患者出现胃食管反流症状,但 2 例(8.6%(2/23):M 级和 A 级)在随访 6 个月以上时内镜检查发现存在轻度反流。无 B 级或更严重的反流性食管炎患者。1 例(4.3%,1/23)发生吻合口狭窄,经内镜扩张后缓解。与术前体重相比,术后 6 个月时平均体重减轻 7.5%。
我们的食管胃吻合非瓣手缝技术具有良好的效果,可能是 LPG 治疗胃癌的一种可靠的抗反流术式。