Muraoka Atsushi, Kobayashi Masahiko, Kokudo Yasutaka
Department of Surgery, Kagawa Rosai Hospital, 3-3-1 Joto-cho, Marugame, Kagawa, 763-0013, Japan.
World J Surg. 2016 Oct;40(10):2419-24. doi: 10.1007/s00268-016-3510-5.
No standard proximal gastrectomy method for gastric cancer of the upper third of the stomach (UGC) has been established because few of the current methods prevent gastro-esophageal reflux and allow easy postoperative endoscopic surveillance. In the present study, we describe laparoscopic proximal gastrectomy with the hinged double flap method (Kamikawa's method) in detail and examine the short- to medium-term outcomes of this approach, which resulted in excellent postoperative function.
Between 2011 and 2015, 24 patients with early-stage primary UGC underwent laparoscopic proximal gastrectomy with the above-mentioned method. The celiac and hepatic nerves were preserved without pyloroplasty. A hand-sewn esophagogastric anastomosis was produced intracorporeally.
There were no in-hospital deaths, and none of the patients were converted to open surgery. Complications occurred in two patients in the early part of this study (minor anastomotic leakage in one case and an abdominal abscess in the other). None of the patients exhibited symptoms of reflux. Regarding the patients' postoperative endoscopic classifications, 17, 2, and 1 patient were considered to have grade N or M, grade A, and grade B esophagitis, respectively. All of the patients remain alive, and no cases of postoperative bowel obstruction or recurrent cancer have been observed.
This method can be performed safely and achieves excellent outcomes in terms of preventing gastro-esophageal reflux. It deserves further evaluation in a multi-center clinical study.
由于目前几乎没有方法能预防胃食管反流并便于术后内镜监测,因此尚未建立针对胃上部三分之一处胃癌(UGC)的标准近端胃切除术方法。在本研究中,我们详细描述了采用铰链双瓣法(神川法)的腹腔镜近端胃切除术,并研究了该方法的短期至中期结果,其术后功能良好。
2011年至2015年间,24例早期原发性UGC患者采用上述方法接受了腹腔镜近端胃切除术。保留了腹腔干和肝神经,未进行幽门成形术。在体内进行手工缝合的食管胃吻合术。
无院内死亡病例,无一例患者转为开放手术。在本研究早期,2例患者出现并发症(1例为轻微吻合口漏,另1例为腹腔脓肿)。所有患者均未出现反流症状。关于患者术后内镜分类,分别有17例、2例和1例患者被认为患有N级或M级、A级和B级食管炎。所有患者均存活,未观察到术后肠梗阻或复发性癌症病例。
该方法可安全实施,在预防胃食管反流方面取得了良好效果。值得在多中心临床研究中进一步评估。