Health Services Vocational College, Çanakkale Onsekiz Mart University, 17100, Çanakkale, Turkey.
Faculty of Medicine, Çanakkale Onsekiz Mart University, Terzioglu Campus, 17100, Çanakkale, Turkey.
Environ Sci Pollut Res Int. 2020 Sep;27(25):31750-31759. doi: 10.1007/s11356-020-09463-z. Epub 2020 Jun 5.
In the current study, we had two main purposes. Firstly, we aimed to compare genetic damages in the agricultural workers of two different types of environmental conditions including the greenhouse and open fields. Secondly, we aimed to compare genetic damages in the total agricultural workers as the exposed group (greenhouse and open field workers) (n = 114) and the non-exposed control group (n = 98) living in the same area in Canakkale, Turkey. For these purposes, we investigated the incidence of micronucleus (MN), nucleoplasmic bridges (NPBs), and nuclear buds (NBUDs) in peripheral blood lymphocytes. We observed that the frequencies of MN, NPB, and NBUD obtained for the greenhouse workers were statistically significantly higher than those obtained for the open field workers. When the results of the control group were compared with those of the total workers, there were statistically significant differences in terms of MN and NBUD frequencies. We found that age and MN were correlated at a significant level in both the agricultural workers and the control group. The MN frequency of the female workers was 1.5 times greater than that of the male workers, and it was a significant level in the agricultural workers.
在本研究中，我们有两个主要目的。首先，我们旨在比较两种不同环境条件（温室和露天田地）下农业工人的遗传损伤。其次，我们旨在比较生活在土耳其恰纳卡莱同一地区的总农业工人（温室和露天田地工人）（n=114）和非暴露对照组（n=98）的遗传损伤。为此，我们研究了外周血淋巴细胞中的微核（MN）、核质桥（NPB）和核芽（NBUD）的发生率。我们观察到，温室工人的 MN、NPB 和 NBUD 频率明显高于露天田地工人。当将对照组的结果与总工人的结果进行比较时，MN 和 NBUD 频率存在统计学显著差异。我们发现，年龄和 MN 在农业工人和对照组中均呈显著相关。女性工人的 MN 频率是男性工人的 1.5 倍，且在农业工人中具有统计学意义。
