Guangdong Engineering Research Center for Insect Behavior Regulation, College of Agriculture, South China Agricultural University, Guangzhou, 510642, China.
Environ Sci Pollut Res Int. 2020 Sep;27(25):31863-31871. doi: 10.1007/s11356-020-09108-1. Epub 2020 Jun 5.
The Aedes albopictus mosquito is a vector of several deadly diseases of humans and domesticated animals. Usually, synthetic insecticides are used for mosquito control. The excessive use of synthetic insecticides is hazardous for humans and the environment. Therefore, there is a need to develop environment-friendly and novel mosquito larvicides. In the current study, we evaluated larvicidal and bite protection properties of Seriphidium brevifolium essential oil (SBEO) and its active constituents against this mosquito. SBEO and its active constituents, α, β-thujone, and limonene, were toxic to A. albopictus, with LC values of 21.43, 45.99, 47.38, and 49.46 μg/mL. The cream formulation of EO at 5 % (w/v) provided complete protection against mosquito bites until 70 min after application. Among the EO constituents tested, α and β-thujone showed considerable protections against mosquito bites but lower as compared with the whole oil. Furthermore, 1:1 combinations of active constituent α-thujone and β-thujone and 1:1:1 combinations of α-thujone, β-thujone, and limonene displayed a synergistic effect against the larvae. Particularly, the EO and its active constituents were safer to Poecilia reticulata a mosquito predator, with LC ranging from 3934.33 to 14,432.11 μg/mL. Our current study indicated that SBEO and some of its constituents can be used for the control of A. albopictus mosquito, as a novel alternative to hazardous synthetic insecticides and to overcome the problem of increasing insecticides resistance.
白纹伊蚊是人类和家养动物几种致命疾病的传播媒介。通常使用合成杀虫剂来控制蚊子。过量使用合成杀虫剂对人类和环境都有危害。因此，需要开发环保和新型的杀蚊幼虫剂。在本研究中，我们评估了短葶飞蓬精油（SBEO）及其活性成分对这种蚊子的杀幼虫和防叮咬性能。SBEO 及其活性成分α-，β-蒎烯和柠檬烯对 A. albopictus 有毒，LC 值分别为 21.43、45.99、47.38 和 49.46μg/mL。5%（w/v）的精油乳剂可提供完全的防蚊叮咬保护，直至涂抹后 70 分钟。在所测试的精油成分中，α-和β-蒎烯对防蚊叮咬有相当大的保护作用，但比全油的保护作用低。此外，活性成分α-蒎烯和β-蒎烯的 1:1 组合以及α-蒎烯、β-蒎烯和柠檬烯的 1:1:1 组合对幼虫表现出协同作用。特别是，精油及其活性成分对食蚊鱼这种蚊子的捕食者更安全，LC 范围为 3934.33 至 14,432.11μg/mL。我们目前的研究表明，SBEO 和其一些成分可用于控制白纹伊蚊，作为一种危险的合成杀虫剂的替代物，以克服杀虫剂抗性增加的问题。
