Laboratory for Nanobiology, Department of Chemistry, KU Leuven, Celestijnenlaan 200G, 3001 Heverlee, Belgium.
Laboratory for Nanobiology, Department of Chemistry, KU Leuven, Celestijnenlaan 200G, 3001 Heverlee, Belgium.
Int J Biochem Cell Biol. 2020 Aug;125:105761. doi: 10.1016/j.biocel.2020.105761. Epub 2020 Jun 3.
Genetically encoded biosensors are indispensable tools for visualizing the spatiotemporal dynamics of analytes or processes in living cells in vitro and in vivo. Their widespread adaptation has gone hand in hand with the development of sensors for new analytes or processes and improved functionality and robustness. In this review, we highlight some of the recent advances in genetically encoded biosensor development, with a special focus on novel and innovative scaffolds that will lead to new possibilities in the future.
基因编码生物传感器是体外和体内可视化分析物或过程时空动态的不可或缺的工具。它们的广泛应用与新型分析物或过程的传感器的开发以及功能和稳定性的提高是齐头并进的。在这篇综述中，我们重点介绍了基因编码生物传感器开发的一些最新进展，特别关注新颖和创新的支架，这些支架将为未来带来新的可能性。
