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同伴和社区卫生工作者主导的自我管理支持计划对改善中低收入国家成年人糖尿病健康相关结局的有效性:系统评价。

The effectiveness of peer and community health worker-led self-management support programs for improving diabetes health-related outcomes in adults in low- and-middle-income countries: a systematic review.

机构信息

Chronic Disease Initiative for Africa, Cape Town, Western Cape, South Africa.

Department of Medicine, Faculty of Health Science, University of Cape Town, Observatory, Cape Town, Western Cape, 7935, South Africa.

出版信息

Syst Rev. 2020 Jun 6;9(1):133. doi: 10.1186/s13643-020-01377-8.

Abstract

OBJECTIVE

Community-based peer and community health worker-led diabetes self-management programs (COMP-DSMP) can benefit diabetes care, but the supporting evidence has been inadequately assessed. This systematic review explores the nature of COMP-DSMP in low- and middle-income countries' (LMIC) primary care settings and evaluates implementation strategies and diabetes-related health outcomes.

METHODS

We searched the Cochrane Library, PubMed-MEDLINE, SCOPUS, CINAHL PsycINFO Database, International Clinical Trials Registry Platform, Clinicaltrials.gov, Pan African Clinical Trials Registry (PACTR), and HINARI (Health InterNetwork Access to Research Initiative) for studies that evaluated a COMP-DSMP in adults with either type 1 or type 2 diabetes in World Bank-defined LMIC from January 2000 to December 2019. Randomised and non-randomised controlled trials with at least 3 months follow-up and reporting on a behavioural, a primary psychological, and/or a clinical outcome were included. Implementation strategies were analysed using the standardised implementation framework by Proctor et al. Heterogeneity in study designs, outcomes, the scale of measurements, and measurement times precluded meta-analysis; thus, a narrative description of studies is provided.

RESULTS

Of the 702 records identified, eleven studies with 6090 participants were included. COMP-DSMPs were inconsistently associated with improvements in clinical, behavioural, and psychological outcomes. Many of the included studies were evaluated as being of low quality, most had a substantial risk of bias, and there was a significant heterogeneity of the intervention characteristics (for example, peer definition, selection, recruitment, training and type, dose, and duration of delivered intervention), such that generalisation was not possible.

CONCLUSIONS

The level of evidence of this systematic review was considered low according to the GRADE criteria. The existing evidence however does show some improvements in outcomes. We recommend ongoing, but well-designed studies using a framework such as the MRC framework for the development and evaluation of complex interventions to inform the evidence base on the contribution of COMP-DSMP in LMIC.

摘要

目的

以社区为基础的同伴和社区卫生工作者主导的糖尿病自我管理计划(COMP-DSMP)可以有益于糖尿病护理,但支持证据评估不足。本系统评价探讨了 COMP-DSMP 在低收入和中等收入国家(LMIC)初级保健环境中的性质,并评估了实施策略和与糖尿病相关的健康结果。

方法

我们在 Cochrane 图书馆、PubMed-MEDLINE、SCOPUS、CINAHL PsycINFO 数据库、国际临床试验注册平台、Clinicaltrials.gov、泛非临床试验注册处(PACTR)和 HINARI(卫生互联网获取研究倡议)中搜索了 2000 年 1 月至 2019 年 12 月期间在世界银行定义的 LMIC 中评估成人 1 型或 2 型糖尿病的 COMP-DSMP 的研究。包括至少随访 3 个月并报告行为、主要心理和/或临床结果的随机和非随机对照试验。使用 Proctor 等人的标准化实施框架分析实施策略。由于研究设计、结局、测量尺度和测量时间存在异质性,排除了 meta 分析;因此,提供了研究的叙述描述。

结果

在确定的 702 条记录中,有 11 项研究共 6090 名参与者入选。COMP-DSMP 与临床、行为和心理结局的改善不一致。许多纳入的研究被评估为质量较低,大多数存在较大的偏倚风险,干预特征存在显著的异质性(例如,同伴定义、选择、招募、培训以及提供干预的类型、剂量和持续时间),因此无法推广。

结论

根据 GRADE 标准,本系统评价的证据水平被认为较低。然而,现有证据确实显示出一些结局的改善。我们建议继续进行,但设计良好的研究,使用 MRC 框架等框架来开发和评估复杂干预措施,为 COMP-DSMP 在 LMIC 中的贡献提供证据基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33ec/7275531/dddc6ea442ca/13643_2020_1377_Fig1_HTML.jpg

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