Eye Center, Albert-Ludwigs-University of Freiburg, Killianstr. 5, 79106, Freiburg, Germany.
Int Ophthalmol. 2020 Oct;40(10):2617-2625. doi: 10.1007/s10792-020-01442-0. Epub 2020 Jun 6.
Recently, intraoperative optical coherence tomography (iOCT) has evolved in the field of ophthalmic surgery. So far, the use of iOCT was mainly focused to lamellar keratoplasty, especially deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). The aim of this study was to report our experiences with iOCT to introduce new possibilities of this application.
We used iOCT in 18 patients who underwent the following surgeries: DALK, DMEK, penetrating keratoplasty, autologous limbal transplantation, transscleral suture fixation of a posterior chamber lens, pannus removal on corneal surface and newborn investigation in Peters' anomaly. We obtained qualitative video data for all procedures.
With the iOCT, the cannula placement during DALK preparation of the recipient cornea and bubble formation could be visualized to improve the success rate of the big bubble injection. In DMEK, the iOCT enables the visualization of Descemet's membrane removal in the recipient and graft orientation as well as better control of graft attachment. The iOCT enables intraoperative visualization of the graft-host interface during penetrating keratoplasty. During autologous limbal transplantation, transscleral suture fixation of a posterior chamber lens and removal of corneal surface pannus the iOCT is capable of showing the thickness of lamellar preparations to avoid penetrations and to save healthy recipient's tissue.
The iOCT is a helpful device for intraoperative anterior segment imaging not only for DALK and DMEK. It is also beneficial in penetrating keratoplasty and every other form of lamellar preparation during corneoscleral surgery.
近年来,术中光学相干断层扫描(iOCT)在眼科手术领域得到了发展。到目前为止,iOCT 的应用主要集中在板层角膜移植术,特别是深层前板层角膜移植术(DALK)和 Descemet 膜内皮角膜移植术(DMEK)。本研究旨在报告我们使用 iOCT 的经验,介绍该应用的新可能性。
我们在 18 名接受以下手术的患者中使用 iOCT:DALK、DMEK、穿透性角膜移植术、自体角膜缘移植术、后房晶状体巩膜缝线固定术、角膜表面血管翳切除术和 Peters 异常新生儿检查。我们为所有手术获得了定性视频数据。
使用 iOCT 可以可视化 DALK 受体角膜套管的放置和气泡形成,以提高大泡注射的成功率。在 DMEK 中,iOCT 可以可视化受体和移植物中的 Descemet 膜去除以及移植物的定位和更好的控制移植物附着。iOCT 可以在穿透性角膜移植术中可视化移植片 - 宿主界面。在自体角膜缘移植术、后房晶状体巩膜缝线固定术和角膜表面血管翳切除术期间,iOCT 能够显示板层制备的厚度,以避免穿透并保存健康受体组织。
iOCT 是一种有助于术中前节成像的设备,不仅适用于 DALK 和 DMEK。它在穿透性角膜移植术和其他形式的角膜巩膜手术中的板层准备中也有益处。